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DRUG SCREENING: HIGH-SPEED CAPILLARY GAS CHROMATOGRAPHY

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
11391
Program Year/Program:
1992 / SBIR
Agency Tracking Number:
11391
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Ionics International, Inc.
10655 Richmond Avenue, Suite 1 Houston, TX 77042
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 2
Fiscal Year: 1992
Title: DRUG SCREENING: HIGH-SPEED CAPILLARY GAS CHROMATOGRAPHY
Agency: HHS
Contract: N/A
Award Amount: $352,702.00
 

Abstract:

MAJOR PROBLEMS ASSOCIATED WITH THE SCREENING OF BODY FLUIDS FOR DRUGS OF ABUSE INCLUDE THE RELATIVELY LOW SPEED OF ANALYSIS AND THE OFTEN POOR RELIABILITY OF THE GENERATED DATA. CAPILLARY GAS CHROMATOGRAPHY IS ACKNOWLEDGED TO BE SUPERIOR IN PERFORMANCE TO THIN-LAYER CHROMATOGRAPHY AND IMMUNOASSAYS, BUT IT IS GENERALLY TOO SLOW TO BE OF VALUE IN THE SCREENING OF LARGE NUMBERS OF SAMPLES. IONICS RESEARCH, INC., PLANS TO DEVELOP A HIGH-SPEED CAPILLAR GAS CHROMATOGRAPH THAT WOULD BE SUITABLE FOR THE ANALYSIS OF DRUGS OF ABUSE IN JUST A FEW SECONDS. THE HEART OF THE NEW INSTRUMENT WOULD BE A MICROBORE COLUMN WITH AN INTERNAL DIAMETER OF 50MUM OR LESS. TO TAKE ADVANTAGE OF THE ULTIMATE PERFORMANCE OF THIS COLUMN, A REVOLUTIONARY INLET SYSTEM AND LOW-DEAD-VOLUME WILL BE DEVELOPED. HIGH-SPEED CHROMATOGRAOPHY WITH A CONCENTRATION-DEPENDENT DETECTOR HAS THE ADDED ADVANTAGE OF A GREATLY IMPROVED DETECTION LIMIT, SO VERY SMALL SAMPLESOF BODY FLUIDS WOULD BE ADEQUATE FOR ANALYSIS. A PROTOTYPE INSTRUMENT WILL BE CONSTRUCTED AND EVALUATED FOR THE DETERMINATION OF AMPHETAMINES, BARBITURATES, OPIOIDS, AND OTHER DRUGS OF ABUSE IN BODY FLUIDS.

Principal Investigator:


0

Business Contact:

Small Business Information at Submission:

Ionics Research Inc.
10633 Richmond Ave Ste 170 Houston, TX 77042

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No