USA flag logo/image

An Official Website of the United States Government

THE ABILITY TO GROW, MAINTAIN, AND CONDUCT EXPERIMENTS ON CELL CULTURES DERIVED…

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
3072
Program Year/Program:
1985 / SBIR
Agency Tracking Number:
3072
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Karyon Technology, Inc.
333 Providence Hwy. Norwood, MA 02062
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1985
Title: THE ABILITY TO GROW, MAINTAIN, AND CONDUCT EXPERIMENTS ON CELL CULTURES DERIVED FROM BIOPSIES AND SURGICAL SPECIMENS FROM HUMAN CANCER PATIENTS WOULD BE OF POTENTIAL BENEFIT TO ONCOLOGISTS IN THEIR SEARCH FOR, AND SELECTION OF, APPROPRIATE THERAPEUTIC
Agency: HHS
Contract: N/A
Award Amount: $44,800.00
 

Abstract:

THE ABILITY TO GROW, MAINTAIN, AND CONDUCT EXPERIMENTS ON CELL CULTURES DERIVED FROM BIOPSIES AND SURGICAL SPECIMENS FROM HUMAN CANCER PATIENTS WOULD BE OF POTENTIAL BENEFIT TO ONCOLOGISTS IN THEIR SEARCH FOR, AND SELECTION OF, APPROPRIATE THERAPEUTIC MODALITIES USED IN TREATMENT OF THEIR PATIENTS. WE BELIEVE THE USE OF KARYON TECHNOLOGY'S GELTRAP IN VITRO CELL CULTURE SYSTEM WOULD FACILITATE THE GROWTH OF TUMOR CELLS DERIVED FROM SUCH PATIENT SPECIMENS. SIMPLE GEL TECHNOLOGIES HAVE ENABLED KARYON TO SUCCESSFULLY GROW MANY TYPES OF TRANSFORMED/TUMORIGENIC CELL TYPES INCLUDING BOTH SUSPENSION CELLS AND ANCHORAGE-DEPENDENT CELLS IN IN VITRO CULTURE SYSTEMS. THIS SYSTEM WOULD EASILY LEND ITSELF TO INDIVIDUAL ON-SITE ISOLATION AND GROWTH OF THESE CELLS IN A SIMPLE AND EFFICIENT MANNER. GROWTH OF SUFFICIENT NUMBERS OF CELLS IN VITRO CAN BE ACHIEVED TO ENABLE ONE TO CONDUCT CYTOTOXICITY STUDIES. THE GELTRAP SYSTEM WOULD PROVIDE AN ADEQUATE MOLECULAR ENVIRONMENT WHICH CLOSELY RESEMBLES THAT FOUND IN VIVO. THE SYSTEM ALSO FACILITATES THE HANDLING, FEEDING AND GROWTH ASSESSMENT OF SUCH CULTURES.

Principal Investigator:

Martin s. sinacore
PRINCIPAL INVESTIGATOR
6177696970

Business Contact:

Small Business Information at Submission:

Karyon Technology, Inc.
333 Providence Hwy. Norwood, MA 02062

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No