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Company Information:

Company Name: Kitware
City: Clifton Park
State: NY
Zip+4: 12065-
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Website URL: http://www.kitware.com
Phone: (518) 371-3971

Award Totals:

Program/Phase Award Amount ($) Number of Awards
SBIR Phase I $8,403,913.00 47
SBIR Phase II $16,419,655.00 19
STTR Phase I $2,676,983.00 14
STTR Phase II $3,025,276.00 4

Award List:

Graphical Visualization Framework for Representing Uncertainty in Dynamic 3-Dimensional Data

Award Year / Program / Phase: 1998 / SBIR / Phase I
Agency / Branch: DOD / USAF
Principal Investigator: Dr. William J. Schroeder
Award Amount: $94,251.00
Abstract:
Although visualization is a provent technology for communicating complex and/or voluminous information, one significant problem is its inability to display information describing data uncertainty. This deficiency has negative on analyzing or assessing data, since the integrity or quality of data is… More

Visualizing Arbitrary Basis Functions for Advanced Engineering Analysis and Simulation

Award Year / Program / Phase: 2002 / SBIR / Phase I
Agency: NSF
Principal Investigator: William Schroeder
Award Amount: $100,000.00
Abstract:
This Small Business Innovation Research (SBIR) Phase I project addresses the lack of visualization technology for advanced engineering simulation tools. Such tools routinely depend on interpolation and approximation (basis) functions for a variety of purposes, including modeling geometry via CAD/CAM… More

Web-based Techniques for Remote Scientific Visualization

Award Year / Program / Phase: 2002 / SBIR / Phase I
Agency / Branch: DOD / ARMY
Principal Investigator: C. Charles Law, Vice President
Award Amount: $119,994.00
Abstract:
"The objective of this Phase I proposal is to design and prototype a web-based visualization system to aid in the analysis of High Performance Computing (HPC) simulations. HPC simulations are widely used in the design of new materials and weapons systems.However, the amount of data they generate… More

Web-based Techniques for Remote Scientific Visualization

Award Year / Program / Phase: 2003 / SBIR / Phase II
Agency / Branch: DOD / ARMY
Principal Investigator: Christopher Law, Vice President
Award Amount: $728,007.00
Abstract:
The objective of this Phase II proposal is to design and implement a web-based visualization system to aid in the analysis of High Performance Computing (HPC) simulations. HPC simulations are widely used in the design of new materials and weaponssystems. However, the amount of data they generate… More

Scalable Grid Technologies for Visualization Services

Award Year / Program / Phase: 2003 / SBIR / Phase I
Agency: DOE
Principal Investigator: William J. Schroeder
Award Amount: $100,000.00
Abstract:
72388S03-I Large-scale computing is increasingly a distributed activity. Expensive and specialized resources ¿ whether they are supercomputers, scientific instrumentation, visualization devices, collaboration facilities, or personnel ¿ are distributed geographically and across organizations. … More

SBIR Phase II: Visualizing Arbitrary Basis Functions for Advanced Engineering Analysis and Simulation

Award Year / Program / Phase: 2003 / SBIR / Phase II
Agency: NSF
Principal Investigator: William Schroeder
Award Amount: $500,000.00
Abstract:
This Small Business Innovative Research Phase II project will create general-purpose software tools for visualizing the results of advanced numerical simulation. Simulation techniques, which make up a large part of the multi-billion dollar CAD/CAM/CAE market, are widely used to design and build the… More

SBIR Phase II: Visualizing Arbitrary Basis Functions for Advanced Engineering Analysis and Simulation

Award Year / Program / Phase: 2003 / SBIR / Phase I
Agency: NSF
Principal Investigator: William Schroeder
Award Amount: $0.00
Abstract:
This Small Business Innovative Research Phase II project will create general-purpose software tools for visualizing the results of advanced numerical simulation. Simulation techniques, which make up a large part of the multi-billion dollar CAD/CAM/CAE market, are widely used to design and build the… More

Software Toolkit for Image Guided Surgery

Award Year / Program / Phase: 2003 / STTR / Phase I
Agency: HHS
Research Institution: GEORGETOWN UNIVERSITY
Principal Investigator: Kevin R. Cleary
Award Amount: $99,824.00
RI Contact: N/A
Abstract:
DESCRIPTION (provided by applicant): This Phase I STTR application represents a partnership between a university-based research group (Imaging Science and Information Systems [ISIS] Center, Department of Radiology, Georgetown University) and a small business specializing in open-source software… More

Scalable Grid Technologies for Visualization Services

Award Year / Program / Phase: 2004 / SBIR / Phase II
Agency: DOE
Principal Investigator: William J. Schroeder, Dr.
Award Amount: $749,869.00
Abstract:
72388-Large-scale computing is increasingly a distributed activity. Expensive and specialized resources ¿ whether they are supercomputers, scientific instrumentation, visualization devices, collaboration facilities, or personnel ¿ are distributed geographically and across organizations. Grid… More

SBIR Phase II: The Visual Database: Portable, Extensive Markup Language (XML)-Based Middleware For Media Representation, Interaction and Exchange

Award Year / Program / Phase: 2004 / SBIR / Phase I
Agency: NSF
Principal Investigator: William J. Schroeder, Dr
Award Amount: $100,000.00
Abstract:
This Small Business Innovative Research (SBIR) Phase II project will create a portable representational and interaction metaphor for digital media embedded in a 3D context. Popular document technologies remain text oriented-that is, content is organized into pages and viewed in reading order. The… More

SBIR Phase II: The Visual Database: Portable, Extensive Markup Language (XML)-Based Middleware For Media Representation, Interaction and Exchange

Award Year / Program / Phase: 2005 / SBIR / Phase II
Agency: NSF
Principal Investigator: William J. Schroeder, Dr
Award Amount: $470,500.00
Abstract:
This Small Business Innovative Research (SBIR) Phase II project will create a portable representational and interaction metaphor for digital media embedded in a 3D context. Popular document technologies remain text oriented-that is, content is organized into pages and viewed in reading order. The… More

SBIR Phase I: Visualization of Massive Multivariate Adaptive Mesh Refinement (AMR) Data

Award Year / Program / Phase: 2005 / SBIR / Phase I
Agency: NSF
Principal Investigator: Lisa S. Avila, Dr
Award Amount: $100,000.00
Abstract:
This Small Business Innovation Research (SBIR) Phase I project addresses the lack of visualization technology for hierarchical overlapping structured grids created through a process known as Adaptive Mesh Refinement (AMR). Although the AMR structure makes possible simulations that would have… More

Rapid, Hardware Accelerated, Large Data Visualization

Award Year / Program / Phase: 2005 / STTR / Phase I
Agency / Branch: DOD / ARMY
Research Institution: UNIV. OF MARYLAND
Principal Investigator: Andrej Cedilnik, Senior Software Engineer
Award Amount: $100,000.00
RI Contact: Amitabh Varshney
Abstract:
Scientists and engineers use computer simulation to model the behavior of physical phenomena. These simulation techniques often produce prodigious amounts of output data. In order to view results, interactive visualization is used since it provides the ability to visually inspect data and… More

SBIR Phase II: Visualization of Massive Multivariate Adaptive Mesh Refinement (AMR) Data

Award Year / Program / Phase: 2006 / SBIR / Phase II
Agency: NSF
Principal Investigator: Lisa S. Avila, Dr
Award Amount: $430,385.00
Abstract:
This Small Business Innovation Research (SBIR) Phase II project addresses the lack of visualization technology for hierarchical structured grids created through an advanced simulation process known as Adaptive Mesh Refinement (AMR). Although the AMR structure makes possible simulations that are too… More

Rapid, Hardware Accelerated, Large Data Visualization

Award Year / Program / Phase: 2006 / STTR / Phase II
Agency / Branch: DOD / ARMY
Research Institution: UNIV. OF MARYLAND
Principal Investigator: Andrej Cedilnik, Project Lead
Award Amount: $749,999.00
RI Contact: Jeff Richardson
Abstract:
The field of scientific simulation is one that is actively evolving, with many commercial and research applications developed to solve a wide array of problems. The results are typically complex, three-dimensional structures containing a variety of scalar

Generating Labeled Voxelizations for Numerical Simulation

Award Year / Program / Phase: 2006 / SBIR / Phase I
Agency / Branch: DOD / USAF
Principal Investigator: William J. Schroeder, President
Award Amount: $99,093.00
Abstract:
Recent advances in imaging systems such as MRI, CT, and PET enable rapid acquisition of biological data. These data are suitable for a variety of simulation techniques, including characterizing the response of biological systems to directed energy. However, these simulations are hampered by the… More

Wide Area Video Image Storage Techniques

Award Year / Program / Phase: 2007 / SBIR / Phase I
Agency / Branch: DOD / DARPA
Principal Investigator: William Hoffman, Vice President
Award Amount: $98,958.00
Abstract:
Very large aerial video collectors (VLAVCs) are of increasing interest, such as Constant Hawk, Sonoma, Angel Fire and the planned ARGUS video sensor. These sensors can generate tremendous amounts of data. This proposal addresses the issue of how to efficiently compress video streams from such… More

Computational Fluid Dynamics Co-processing for Unsteady Visualization

Award Year / Program / Phase: 2007 / SBIR / Phase I
Agency / Branch: DOD / ARMY
Principal Investigator: Berk Geveci, Project Lead
Award Amount: $69,922.00
Abstract:
Data management is a major bottle neck in exploitation of simulations for predicting and analyzing complex fluid dynamics. We propose creating a co-processing toolkit that extracts significant features from simulation results as the simulation is running. This toolkit will allow analysis of fine… More

High Throughput web-base Image Analysis of Mouse Brain MR Imaging Studies

Award Year / Program / Phase: 2007 / STTR / Phase I
Agency: HHS
Research Institution: UNC- CHAPEL HILL
Principal Investigator: Martin A. Styner
Award Amount: $396,939.00
RI Contact: N/A
Abstract:
DESCRIPTION (provided by applicant): In the last decade, MRI studies of human brain morphometry have been used to investigate a multitude of pathologies and drug-related effects in psychiatric research. The morphometric measures that differentiate patient populations or track longitudinal changes… More

Generating Labeled Voxelizations for Numerical Simulation

Award Year / Program / Phase: 2007 / SBIR / Phase II
Agency / Branch: DOD / USAF
Principal Investigator: Stephen Aylward, Chief Medical Scientist
Award Amount: $747,496.00
Abstract:
The goal of the proposed research is to create software applications for segmenting medical images; the segmented images are then voxelized for use in the numerical simulation of directed energy on biological systems. In Phase I we identified segmentation algorithms to be used for different… More

Computer Asistance for Targeting of Small Pulmonary Nodules in CT-Guided Biopsy

Award Year / Program / Phase: 2007 / STTR / Phase I
Agency: HHS
Research Institution: WEILL CORNELL MEDICAL CENTER
Principal Investigator: David F. Yankelevitz
Award Amount: $206,193.00
RI Contact: N/A
Abstract:
DESCRIPTION (provided by applicant): The overall goal of this project is to develop a computer-aided system that can assist the radiologist in targeting small pulmonary nodules during CT-guided lung biopsy. The estimated 3D needle trajectory along with the range of potential needle trajectories… More

Computational Fluid Dynamics Co-processing for Unsteady Visualization

Award Year / Program / Phase: 2008 / SBIR / Phase II
Agency / Branch: DOD / ARMY
Principal Investigator: Berk Geveci, Project Lead
Award Amount: $729,813.00
Abstract:
As numerical simulations have grown in size and complexity, it is becoming increasingly difficult to manage the execution of the computational process and the resulting output data. Kitware proposes a co-processing analysis and visualization framework that greatly improves the ability to monitor and… More

Collaborative Visualization for Large-Scale Accelerator Electromagnetic Modeling

Award Year / Program / Phase: 2008 / SBIR / Phase I
Agency: DOE
Principal Investigator: William J. Schroeder, Dr.
Award Amount: $100,000.00
Abstract:
Large-scale accelerator modeling is vital to the design and optimization of particle accelerators, and visualization is an indispensable component for capturing all relevant effects from the huge amount of simulation data. Yet, most visualization tools are limited to one computer of a single… More

Expert system for coherent feature detection in high-fidelity fluid dynamic simulations

Award Year / Program / Phase: 2009 / STTR / Phase I
Agency / Branch: DOD / USAF
Research Institution: Mississipi State Univeristy
Principal Investigator: David Thompson, Associate Professor
Award Amount: $99,203.00
RI Contact: David Thompson
Abstract:
Current computational fluid dynamics simulations produce large amounts of data. These data have become so large that traditional methods employing manual inspection and visualization cannot effectively process the information. Thus the value of these simulations is diminished because the information… More

Building Recognition by Function

Award Year / Program / Phase: 2009 / STTR / Phase I
Agency / Branch: DOD / DARPA
Research Institution: UNIV. OF PENNSYLVANIA
Principal Investigator: Anthony Hoogs, Director of Computer Vision
Award Amount: $98,884.00
RI Contact: Mark West
Abstract:
The activity surrounding a building can provide functional information that is not available in static imagery. We propose to develop a method to classify buildings based on observed video activity that addresses the primary challenges of noisy, partial observables, and urban environments where… More

Automated DECT Angiography Bone Removal

Award Year / Program / Phase: 2009 / SBIR / Phase I
Agency: HHS
Principal Investigator: Wes Turner
Award Amount: $172,255.00
Abstract:
DESCRIPTION (provided by applicant): This overall goal of this SBIR project is to develop a fully automated bone removal method for Dual Energy Computed Tomography (DECT) angiography scans. Dual energy scans offer the opportunity to better understand the m aterial decomposition of anatomy, thus… More

Vision with a Purpose: Inferring the Function of Objects in Video

Award Year / Program / Phase: 2009 / SBIR / Phase I
Agency / Branch: DOD / DARPA
Principal Investigator: Anthony Hoogs, Director of Computer Vision
Award Amount: $98,527.00
Abstract:
Video provides the opportunity to classify vehicles, people, buildings and other structures by their behavior and the activity surrounding them. Object classes that are visually indistinguishable can be differentiated using activity, even in low-resolution video where traditional recognition from… More

Wide Area Video Image Storage Techniques

Award Year / Program / Phase: 2009 / SBIR / Phase II
Agency / Branch: DOD / DARPA
Principal Investigator: Amitha Perera, Research and Development
Award Amount: $914,647.00
Abstract:
Very large aerial video collectors (VLAVCs) are of increasing interest, including such systems as Constant Hawk, Sonoma, Angel Fire and the planned ARGUS video sensor. These systems show significant potential in their ability to provide surveillance capabilities; however, the amount of data they… More

Human-Robot Instruction for Perceptual Teamwork

Award Year / Program / Phase: 2009 / SBIR / Phase I
Agency / Branch: DOD / DARPA
Principal Investigator: Anthony Hoogs, Director of Computer Vision
Award Amount: $98,856.00
Abstract:
The utility of mobile robots would be greatly enhanced if they could be taught how to be competent, helpful members of military teams in the field. We propose a method for human instruction of robots, where the instructor teaches the robot how to recognize common situations and activities… More

Tracking Everything Around Me

Award Year / Program / Phase: 2009 / SBIR / Phase I
Agency / Branch: DOD / DARPA
Principal Investigator: Anthony Hoogs, Director of Computer Vision
Award Amount: $98,461.00
Abstract:
We propose to develop and conduct initial evaluations of real time computer vision algorithms for detecting and tracking people and other movers from robot mounted video cameras. The rapid sensor motion and depth of field motivates the use of direct shape and appearance-based methods for detection… More

Scalable and Temporal Data Analytics for Mobile ad

Award Year / Program / Phase: 2009 / SBIR / Phase I
Agency / Branch: DOD / ARMY
Principal Investigator: Jeffrey Baumes, R&D Engineer
Award Amount: $69,473.00
Abstract:
Digital communications are vital to success on the modern battlefield. However, the abundance of networked resources, especially their ad hoc, dynamic character, introduces potential vulnerabilities including traffic overload and the formation of critical nodes. In order to manage these resources… More

Tracking the Little Things in Big Urban Scenes

Award Year / Program / Phase: 2009 / SBIR / Phase I
Agency / Branch: DOD / DARPA
Principal Investigator: Amitha Perera, Research Scientist
Award Amount: $98,994.00
Abstract:
Detecting and tracking dismounts in wide-area aerial video is a challenging task because of low resolution, parallax, occlusions from buildings and other structures, nuisance motion, and low frame rate on some sensors. We propose a multi-target tracking system that will robustly track dismounts and… More

Super 3D from Video

Award Year / Program / Phase: 2009 / SBIR / Phase I
Agency / Branch: DOD / DARPA
Principal Investigator: Amitha Perera, Research Scientist
Award Amount: $98,950.00
Abstract:
We propose to develop a novel approach to extracting 3D structure from wide-area video with sub-pixel accuracy. Multiple redundant video frames from very similar viewpoints enable super-resolution, while multiple frames from separated viewpoints enable 3D structure estimation. In our approach we… More

Management and Comparative Analysis of Dataset Ensembles

Award Year / Program / Phase: 2009 / SBIR / Phase I
Agency: DOE
Principal Investigator: Berk Geveci, Dr.
Award Amount: $99,857.00
Abstract:
Simulation and experimental data is growing in size and complexity. Furthermore, the number of datasets that must be analyzed and compared with one another is increasing. These increases in data size and complexity are negatively impacting the use of modern computer simulation methods, since… More

Multi-Resolution Streaming for Remote Scalable Visualization

Award Year / Program / Phase: 2009 / SBIR / Phase I
Agency: DOE
Principal Investigator: Charles Law, Dr.
Award Amount: $99,467.00
Abstract:
With larger computers producing unprecedented amounts of data, data sizes are now approaching petascale. This poses problems to scientists and engineers who wish to view the data. While in the past it was feasible to copy data from a supercomputer to a local computing center for follow-on… More

Collaborative Visualization for Large-Scale Accelerator Electromagnetic Modeling

Award Year / Program / Phase: 2009 / SBIR / Phase II
Agency: DOE
Principal Investigator: William J. Schroeder, Dr.
Award Amount: $749,546.00
Abstract:
As the complexity and scale of numerical simulation and experimentation increases, larger teams of researchers and scientists, located at geographically different sites, are required to address the resulting technical challenges. The success of research projects typically requires that such teams,… More

Flexible information visualization and analysis platform for biomedical research

Award Year / Program / Phase: 2009 / SBIR / Phase I
Agency: HHS
Principal Investigator: Wes Turner
Award Amount: $300,000.00
Abstract:
DESCRIPTION (provided by applicant): The information age is a term that has come of age; with information generation and consumption being central to our daily lives and paramount to any scientific endeavor. However, information without structure is onl y noise. The science of information, … More

Using Stylistic Topic Models to Detect Deception Through Unusual Linguistic Activity

Award Year / Program / Phase: 2010 / STTR / Phase I
Agency / Branch: DOD / NAVY
Research Institution: UC Irvine
Principal Investigator: Jeffrey Baumes, Technical Lead
Award Amount: $69,997.00
RI Contact: Allison Crowther-Ramos
Abstract:
Analysts are faced with the challenge of sifting through enormous quantities of documents, blog posts, communications, etc. to find deceptive behaviors. We propose novel techniques for efficiently and automatically detecting deception on large data with high accuracy by using methodologies from both… More

Building Recognition by Function

Award Year / Program / Phase: 2010 / STTR / Phase II
Agency / Branch: DOD / DARPA
Research Institution: University of Pennsylvania
Principal Investigator: Anthony Hoogs, Director of Computer Vision – (518) 881-4910
Award Amount: $749,406.00
RI Contact: Mark West
Abstract:
The goal of BLUE is to identify the function or purpose of buildings using persistant surveillance video such as Constant Hawk or Angel Fire. In Phase 1, we developed preliminary algorithms demonstrating that functional recognition of buildings and other scene elements such as parking spots and… More

Discovery of Human Activity from Video

Award Year / Program / Phase: 2010 / SBIR / Phase I
Agency / Branch: DOD / OSD
Principal Investigator: Anthony Hoogs, Director of Computer Vision
Award Amount: $99,981.00
Abstract:
We propose to develop a video analysis system that detects suspicious, significant events using two methods: monitoring current activity against learned models of normal behavior, and searching for events explicitly indicated by the video analyst. The underlying behavior representations are based on… More

An Open, Adaptive Geospatial Visual Information System

Award Year / Program / Phase: 2010 / SBIR / Phase I
Agency / Branch: DOD / DARPA
Principal Investigator: Jeffrey Baumes, R&D Engineer
Award Amount: $98,829.00
Abstract:
The military has an increasing amount and variety of data sources collected using state-of-the-art technologies. Further, there is rapid proliferation of handheld devices, meaning that every soldier may become a sensor and require access to the information stream. Such a rich information environment… More

Approach-specific, multi-GPU, multi-tool, high-realism neurosurgery simulation

Award Year / Program / Phase: 2010 / SBIR / Phase I
Agency: HHS
Principal Investigator: Michel A. Audette
Award Amount: $573,046.00
Abstract:
DESCRIPTION (provided by applicant): Simulation has made limited inroads in neurosurgery, despite validation studies demonstrating its advantages over traditional training. It has emphasized needle insertion and failed to address requirements of surgeons-i n-training on most future caseloads.… More

Scalable computational tools for reverse engineering neural circuits from histolo

Award Year / Program / Phase: 2010 / SBIR / Phase I
Agency: HHS
Principal Investigator: Christopher C. Law
Award Amount: $498,419.00
Abstract:
DESCRIPTION (provided by applicant): We propose to develop the computational infrastructure necessary for future large-scale reverse engineering of cortical circuits. Neuroscience researchers are using confocal and electron micrograph (EM) techniques to s can neural tissue at high resolution. Their… More

Vision with a Purpose: Inferring the Function of Objects in Video

Award Year / Program / Phase: 2010 / SBIR / Phase II
Agency: DOD
Principal Investigator: Matt Turek, Research Scientist – (518) 881-4942
Award Amount: $749,950.00
Abstract:
On Phase 1, we developed an approach to functional object recognition that learns functional models from video tracks in an unsupervised fashion. On Phase 2, we will expand the algorithms and concepts developed on Phase 1 into a comprehensive prototype system that performs functional object… More

Super 3D from Video

Award Year / Program / Phase: 2010 / SBIR / Phase II
Agency / Branch: DOD / DARPA
Principal Investigator: Amitha Perera, Research Scientist
Award Amount: $749,916.00
Abstract:
We propose to develop a novel approach to extracting 3D structure from wide-area video with sub-pixel accuracy. Multiple redundant video frames from very similar viewpoints enable super-resolution, while multiple frames from separated viewpoints enable 3D structure estimation. In our approach we… More

Open, Cross Platform Chemistry Application

Award Year / Program / Phase: 2010 / SBIR / Phase I
Agency / Branch: DOD / ARMY
Principal Investigator: Marcus Hanwell, R&D Engineer
Award Amount: $69,987.00
Abstract:
This project aims to create an open, cross platform desktop application for chemistry. The focus in Phase I will be on developing a prototype application around stand-alone programs and databases used by ERDC researchers in connection with environmentally important aspects of military compounds.… More

Human-Robot Instruction for Perceptual Teamwork

Award Year / Program / Phase: 2010 / SBIR / Phase II
Agency / Branch: DOD / DARPA
Principal Investigator: Anthony Hoogs, Director of Computer Visi
Award Amount: $749,532.00
Abstract:
The main result of the proposed research program will be an integrated activity recognition and modeling software system that will operate on-board a mobile robot equipped with video cameras, and operating in highly dynamic and cluttered environments. The software will include a user feedback… More

A Scalable Visual System For Proliferation Analysis

Award Year / Program / Phase: 2010 / SBIR / Phase I
Agency: DOE
Principal Investigator: Jeffrey Baumes, Dr.
Award Amount: $100,000.00
Abstract:
There may never be a time in the future where the threat of nuclear proliferation ceases to exist. Due to the sheer power and potential destruction these weapons possess, the global community must keep a vigilant watch on the spread of this technology. This will remain a critical factor in securing… More

Web-Based Scientific Collaboratory for Large Data Analysis

Award Year / Program / Phase: 2010 / SBIR / Phase I
Agency: DOE
Principal Investigator: Berk Geveci, Dr.
Award Amount: $100,000.00
Abstract:
Simulation and experimental data is growing in size and complexity. As a result it is difficult to understand and leverage the value of these data. Thus new methods of analyzing and processing data must be found if we are to benefit from the wealth of data available now, not to mention the flood of… More

Improving liver lesion biopsy in the CT suite through fusion with PET images

Award Year / Program / Phase: 2010 / STTR / Phase I
Agency: HHS
Research Institution: George Washington University
Principal Investigator: Kevin R. Cleary – 202-476-3809
Award Amount: $228,458.00
RI Contact:
Abstract:
DESCRIPTION (provided by applicant): The broad objective of this proposal is to improve the clinical effectiveness of liver lesion biopsy by fusing respiratory-compensated PET with CT images in the CT suite. On CT imaging alone, localization of liver lesions can potentially be challenging,… More

Web-Based Infrastructure for Comparison and Validation of Image Computing Methods

Award Year / Program / Phase: 2010 / STTR / Phase I
Agency: HHS
Research Institution: University Of Utah
Principal Investigator: Stephen R. Aylward – 518-371-3971
Award Amount: $237,264.00
RI Contact:
Abstract:
DESCRIPTION (provided by applicant): Validation of computing algorithms has been a challenging topic over the last few years. In fact, several international workshops in the medical imaging field started to involve the community through grand challenges .A grand challenge involves selecting driving… More

An Open Source Digital Pathology System Supporting Multi-Touch Interaction

Award Year / Program / Phase: 2011 / SBIR / Phase I
Agency: HHS
Principal Investigator: Christopher C. Law – 518-371-3971
Award Amount: $149,353.00
Abstract:
DESCRIPTION (provided by applicant): Medical records are being digitized in order to improve patient care, and the integrated digitization of all components of the medical record will also help reduce the number of errors and reduce health care costs. Images form part of the medical record. In some… More

Robot-assisted prostate surgery using augmented reality with deformable models

Award Year / Program / Phase: 2011 / SBIR / Phase I
Agency: HHS
Principal Investigator: Andinet A. Enquobahrie – 518-371-3971
Award Amount: $100,000.00
Abstract:
DESCRIPTION (provided by applicant): In this application, we describe our proposed work to develop an augmented display for improved visualization of the prostate and surrounding critical anatomy for robot-assisted prostate surgery. Prostate cancer is the second leading cause of cancer-related… More

Large-Scale Time Lapse Imaging to Monitor Neuroplasticity and Circuit Function

Award Year / Program / Phase: 2011 / SBIR / Phase I
Agency: HHS
Principal Investigator: Christopher C. Law – 518-881-4904
Award Amount: $149,574.00
Abstract:
DESCRIPTION (provided by applicant): We propose to develop an open-source software system that will manage acquisition, storage and retrieval of very large time-lapse microscopy datasets. High-resolution wide-field images will be constructed from multipleimages tiles, and the images will be… More

Scalable ParaView for Extreme Scale Visualization

Award Year / Program / Phase: 2011 / SBIR / Phase I
Agency: NASA
Principal Investigator: Utkarsh Ayachit, Principal Investigator
Award Amount: $99,693.00
Abstract:
Petscale computing is leading to significant breakthroughs in a number of fields and is revolutionizing the way science is conducted. Data is not knowledge, however, and the challenge has been how to analyze and gain insight from the massive quantities of data that are generated. In order to… More

ClimatePipes: User-Friendly Data Access, Data Manipulation, Data Analysis and Visualization of Community Climate Models

Award Year / Program / Phase: 2011 / SBIR / Phase I
Agency: DOE
Principal Investigator: Berk Geveci, Dr. – 518-371-3971
Award Amount: $150,000.00
Abstract:
The aim of this proposal is to facilitate the access that non-researchers have to data generated from high-resolution, long-term, climate change projections performed as part of the U.S. Global Change Research Program. Effective analysis in climate science depends on having the appropriate cyber… More

Landmark Navigation for Unmanned Ground Vehicles

Award Year / Program / Phase: 2012 / STTR / Phase I
Agency / Branch: DOD / ARMY
Research Institution: Texas Engineering Experiment Statio
Principal Investigator: Amitha Perera, Technical Leader – (518) 881-4940
Award Amount: $98,418.00
RI Contact: Heather Henry
Abstract:
We propose a novel robot navigation paradigm based on high-level visual landmarks, including structural landmarks and object-level landmarks. The system will use our novel multilayered-feature graph (MFG) to combine multiple, heterogeneous features (from points to planes to vanishing points)… More

Scalable Software for Reverse Engineering Neural Circuits from Histology

Award Year / Program / Phase: 2012 / SBIR / Phase II
Agency: HHS
Principal Investigator: Christopher C. Law – 518-371-3971
Award Amount: $985,951.00
Abstract:
DESCRIPTION (provided by applicant): A human brain is estimated to have roughly 100 billion neurons connected through more than 100 thousand miles of axons and a quadrillion of synaptic connections (~10 15 or 2 50 connections). As a comparison, there aremore synaptic connections in human brains in… More

ClimatePipes: User-Friendly Data Access, Data Manipulation, Data Analysis and Visualization of Community Climate Models

Award Year / Program / Phase: 2012 / SBIR / Phase II
Agency: DOE
Principal Investigator: Berk Geveci, Dr. – 518-371-3971
Award Amount: $999,999.00
Abstract:
Observations unequivocally show that the global climate is changing and the results are dramatic. With the accelerating pace of climate change, the impact of these changes will resonate through a broad range of fields including public health, infrastructure, water resources, and many others. These… More

Graphical HPC Application Suite for Supporting the Product Simulation Lifecycles

Award Year / Program / Phase: 2012 / SBIR / Phase I
Agency: DOE
Principal Investigator: Robert O'Bara, Dr. – 518-371-3971
Award Amount: $149,809.00
Abstract:
The integration of Computer Aided Design (CAD) and Computer Aided Engineering (CAE) into the product design and manufacturing process has shown to be a major benefit in terms of reducing both time and cost as well as increasing reliability. However, based on current practices the full potential of… More

Cloud Computing and Visualization Tools for KBase

Award Year / Program / Phase: 2012 / SBIR / Phase I
Agency: DOE
Principal Investigator: Jeffrey Baumes, Dr. – 518-371-3971
Award Amount: $149,389.00
Abstract:
It is becoming abundantly clear that the scientific world is being saturated by its own data, with raw data collection increasingly outpacing researchers ability to extract meaningful knowledge from it. Nowhere is this more apparent than in the proliferation of omics fields, which are generating… More

In-Situ Analysis of Cosmological Simulations

Award Year / Program / Phase: 2012 / SBIR / Phase I
Agency: DOE
Principal Investigator: Berk Geveci, Dr. – 518-371-3971
Award Amount: $149,931.00
Abstract:
Cosmological simulations play a very important role in the DOE High Energy Physics Cosmic Frontier program. They are used to connect fundamental physics with observation, and are especially critical in the effort to understand Dark Energy. Current and upcoming cosmological observations that survey… More

Calibrated Methods for Quantitative PET/CT Imaging

Award Year / Program / Phase: 2012 / STTR / Phase I
Agency: HHS
Research Institution: UNIVERSITY OF WASHINGTON
Principal Investigator: Rick Avila – 518-371-3971
Award Amount: $247,137.00
RI Contact:
Abstract:
DESCRIPTION (provided by applicant): The overall goal of this STTR project is to develop calibrated 3D quantitative analysis tools that directly support improved quantitative accuracy in clinical trials using PET/CT imaging. Pocket phantom technology willbe extended to characterize, perform quality… More

Improving liver lesion biopsy in the CT suite through fusion with PET images

Award Year / Program / Phase: 2012 / STTR / Phase II
Agency: HHS
Research Institution: GEORGETOWN UNIVERSITY
Principal Investigator: Kevin R. Cleary – 202-476-3809
Award Amount: $814,246.00
RI Contact:
Abstract:
DESCRIPTION (provided by applicant): PET imaging provides information on functional or metabolic characteristics of tumors, whereas CT predominately assesses tumor's anatomical and morphological features. Given the ability of PET to localize malignancies in situations where the same tumors do… More

Adaptive, Automated Real-time Event/Target Detection using Supervised Learning

Award Year / Program / Phase: 2012 / SBIR / Phase I
Agency: DOD
Principal Investigator: Harry Sun, Senior Research Engineer – (518) 836-2192
Award Amount: $79,994.00
Abstract:
Automatic event and activity recognition from stream video and video archive can greatly enhance the effectiveness and efficiency of motion imagery analyst by filtering out the most relevant and timely content from a huge amount of video data through query video clips. Building on our DARPA VIRAT… More

Open, Cross Platform Chemistry Application

Award Year / Program / Phase: 2012 / SBIR / Phase II
Agency / Branch: DOD / ARMY
Principal Investigator: Marcus Hanwell, Researcher – (518) 371-3971
Award Amount: $721,573.00
Abstract:
The proposed work aims to create an extensible, open, cross-platform desktop chemistry workbench. The focus of this Phase II proposal will be on developing a suite of loosely coupled applications to access standalone programs and databases used by ERDC researchers in connection with environmentally… More

Quantitative ultrasound analysis of vascular morphology for cancer assessment

Award Year / Program / Phase: 2012 / SBIR / Phase I
Agency: HHS
Principal Investigator: Stephen R. Aylward – 518-371-3971
Award Amount: $298,436.00
Abstract:
DESCRIPTION (provided by applicant): There are several features of ultrasound as an imaging modality that make it attractive to clinicians and preclinical researchers today, including its relatively low cost, real-time imaging capability, safety, and portability. These facets make it a particularly… More

FAST TRACK: Open-Source Integrated Design-Analysis Environment for Nuclear Energy Advanced Modeling and Simulation

Award Year / Program / Phase: 2013 / SBIR / Phase I
Agency: DOE
Principal Investigator: Patrick O'Leary, Dr.
Award Amount: $1,724,998.00
Abstract:
In 2011, the US electricity generation was 4344 billion kWh gross with 821 TWh (19%) from nuclear power reactors. The US has 104 nuclear power reactors, 69 pressurized water reactors and 35 boiling water reactors, in 31 states, operated by 30 different power companies. Almost all of the US nuclear… More

Learning the Language of Healthcare: Enabling Semantic Web Technology in CHCS

Award Year / Program / Phase: 2013 / SBIR / Phase I
Agency: DOD
Principal Investigator: Wes Turner, Technical Leader – (518) 371-3971
Award Amount: $149,983.00
Abstract:
The goal of this project is to implement a Universal Exchange Language suitable for nationwide adoption across healthcare providers, and accessible to patients and medical researchers under appropriate protections for security and privacy, as envisioned in the 2010 PCAST report on Health Information… More

Graphical HPC Application Suite for Supporting the Product Simulation Lifecycles

Award Year / Program / Phase: 2013 / SBIR / Phase II
Agency: DOE
Principal Investigator: Robert O'Bara, Dr.
Award Amount: $1,000,000.00
Abstract:
The manufacturing and engineering industry needs more cost effective and easy-to-use high- performance computing (HPC) modeling and simulation tools to design, test, and analyze innovative components and products. For 92% of the small- to medium-sized manufacturers with less than 100… More

A Framework for In Situ Analysis and Visualization of Large-Scale Cosmology Simulations

Award Year / Program / Phase: 2013 / SBIR / Phase II
Agency: DOE
Principal Investigator: Berk Geveci, Dr.
Award Amount: $999,997.00
Abstract:
Numerical simulations play a crucial role in the DOE High Energy Physics (HEP) Cosmic Frontier program. They provide a theoretical framework with which to compare observational data from surveys. Through such comparisons, significant breakthroughs are made. These breakthroughs can guide scientists… More

Efficient Model Posing and Morphing Software

Award Year / Program / Phase: 2013 / SBIR / Phase I
Agency / Branch: DOD / USAF
Principal Investigator: Stephen Aylward, Dr. Director of Operations, NC – (518) 371-3971
Award Amount: $149,912.00
Abstract:
ABSTRACT: Studying the effects of electromagnetic energies on human anatomy requires the consideration how the effects change for different anatomical poses and body types, e.g., for different body-mass indexes. Acquiring such a wide range of data, however, can be problematic given medical scanner… More

MAP-Tk: Motion Imagery Aerial Photogrammetry Toolkit

Award Year / Program / Phase: 2013 / SBIR / Phase I
Agency: DOD
Principal Investigator: Matthew Leotta, Research and Development Engineer – (518) 371-3971
Award Amount: $149,963.00
Abstract:
ABSTRACT: Kitware proposes MAP-Tk, the open-source Motion imagery Aerial Photogrammetry Toolkit, designed for optimized sparse bundle adjustment (SBA) of FMV and WAMI. Our proposed toolkit has a highly configurable and modular design supporting interchange of existing solutions for feature… More

Image-Based Quantification and Analysis of Longitudinal Lung Nodule Deformations

Award Year / Program / Phase: 2013 / STTR / Phase I
Agency: HHS
Research Institution: ROCHESTER INSTITUTE OF TECHNOLOGY
Principal Investigator: Nathan D. Cahill – 585-475-5144
Award Amount: $397,990.00
RI Contact:
Abstract:
DESCRIPTION (provided by applicant): Image-based evaluation of pathologies over time is complicated by variability in image acquisition and patient positioning, deformations due to respiratory and cardiac motion, and the clinical standard in radiology of comparing unaligned images. This application… More

Multimodality image-based assessment system for traumatic brain injury

Award Year / Program / Phase: 2013 / STTR / Phase I
Agency: HHS
Research Institution: REGENTS OF THE UNIVERSITY OF CA AND U. OF NC
Principal Investigator: Stephen R. Aylward – 518-371-3971
Award Amount: $296,676.00
RI Contact:
Abstract:
DESCRIPTION (provided by applicant): Nearly 1.7 million Americans suffer traumatic brain injury (TBI) annually, which constitutes an important and significant US medical health concern. Although neuroimaging plays an important role in pathology localization and surgical planning, TBI clinical care… More

Performance Improvement Technology in Urban Native American Health Organizations

Award Year / Program / Phase: 2013 / SBIR / Phase I
Agency: HHS
Principal Investigator: Stephen R. Aylward – 518-371-3971
Award Amount: $395,709.00
Abstract:
DESCRIPTION (provided by applicant): The Focused Assessment with Sonography for Trauma (FAST) procedure is an ultrasound examination performed to identify intra-peritoneal hemorrhage or pericardial tamponade. FAST involves the detection of free fluid in ultrasound images from four specific abdominal… More

An Open Source Digital Pathology System Supporting Multi-Touch Interaction

Award Year / Program / Phase: 2013 / SBIR / Phase II
Agency: HHS
Principal Investigator: Christopher C. Law – 518-881-4904
Award Amount: $1,510,243.00
Abstract:
DESCRIPTION (provided by applicant): This application addresses Innovations in Biomedical Computational Science and Technology Initiative PAR-09-220. Healthcare is moving towards fully digitized patient records. Surgical pathology represents a challenge inthat high resolution imaging of tissue… More

Approach-specific, multi-GPU, multi-tool, high-realism neurosurgery simulation

Award Year / Program / Phase: 2013 / SBIR / Phase II
Agency: HHS
Principal Investigator: Andinet A. Enquobahrie – 518-371-3971
Award Amount: $1,932,231.00
Abstract:
DESCRIPTION (provided by applicant): Approach-specific, Multi-GPU, Multi-tool, High-realism Neurosurgery Simulation Surgical treatment of neurological diseases is complicated and requires advanced training. However, compressed internship schedules in hospitals creates a challenge to young surgeons… More

Open-Source Visualization and Analysis Platform for 3D Reconstructions of Materials by Transmission Electron Microscopy

Award Year / Program / Phase: 2014 / SBIR / Phase I
Agency: DOE
Principal Investigator: Marcus Hanwell, Dr.
Award Amount: $150,000.00
Abstract:
Three-dimensional characterization of materials at the nano- and meso-scale has become possible with transmission and scanning transmission electron microscopes. Its importance has extended to a wide class of nanomaterialssuch as hydrogen fuel cells, solar cells, industrial catalysts, new battery… More

Web-Based Computational Model Builder for Nuclear Energy Advanced Modeling and Simulation

Award Year / Program / Phase: 2014 / SBIR / Phase I
Agency: DOE
Principal Investigator: Sebastien Jourdain, Mr.
Award Amount: $149,998.00
Abstract:
According to the World Nuclear Association, the U.S. is the largest producer of nuclear power worldwide. In fact, the U.S. provides over 30 percent of the worlds nuclear generation of electricity. Although few new reactors have been built in the past 30 years, the association anticipates that four… More

Retinal Image Management System (RIMS)

Award Year / Program / Phase: 2014 / SBIR / Phase I
Agency / Branch: DOD / USAF
Principal Investigator: Wesley Turner, Technical Leader – (518) 371-3971
Award Amount: $149,902.00
Abstract:
ABSTRACT: Retinal damage is a debilitating condition, which, if left untreated, can lead to blindness. This condition is widespread and has many causes, ranging from accidental exposure to environmental dangers, to complications of disease such as diabetes (diabetic retinopathy), normal… More

Open-Source, Distributed Computational Environment for Virtual Materials Exploration

Award Year / Program / Phase: 2014 / SBIR / Phase I
Agency / Branch: DOD / USAF
Principal Investigator: Marcus D. Hanwell, Technical Leader – (518) 371-3971
Award Amount: $149,949.00
Abstract:
ABSTRACT: The structural design community regard materials models as fixed inputs to a finite element-based design process, using materials lookup tables to provide data from experimental and/or simulations performed by others. However the accuracy of multiscale materials modeling has improved… More