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CAMERA SYSTEM FOR TWO-DIMENSIONAL ELECTROPHORESIS GELS

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
4951
Program Year/Program:
1988 / SBIR
Agency Tracking Number:
4951
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
LARGE SCALE BIOLOGY CORPORATION
LARGE SCALE BIOLOGY CORPORATION 20451 SENECA MEADOWS PKY GERMANTOWN, MD 20876 0700
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 2
Fiscal Year: 1988
Title: CAMERA SYSTEM FOR TWO-DIMENSIONAL ELECTROPHORESIS GELS
Agency: HHS
Contract: N/A
Award Amount: $500,000.00
 

Abstract:

WHILE A VARIETY OF SCANNERS AND CAMERA SYSTEMS HAVE BEEN DESCRIBED FOR ACQUIRING TWO-DIMENSIONAL ELECTROPHORETIC GEL PATTERNS FOR DISPLAY, ANALYSIS, INTERCOMPARISON, AND REPRODUCTION, NONE SOLVES ALL OF THE PROBLEMS OF IMAGE ACQUISITION AND IMAGE IDENTIFICATION IN A SATISFACTORY MANNER. THIS PROPOSAL IS FOR THE DEVELOPMENT OF A 70-MM PRECISION PIN-REGISTERED CAMERA SYSTEM FOR PHOTOGRAPHING TWO-DIMENSIONAL ELECTROPHORETIC PATTERNS. A SECOND OPTICAL PATH INCLUDES IN THE NEGATIVE A CRT-GENERATED IDENTIFICATIONAND DATA DISPLAY AREA. A UNIQUE DESIGN REDUCES LENS FLARE TO A MINIMUM. USING A THREE-COLOR FILTER SYSTEM, COLOR SEPARATION NEGATIVES MAY ALSO BE MADE IN SEQUENCE FOR SUBSEQUENT COLOR REPRODUCTION. THE CAMERA SYSTEM IS ALSO A 70-MM PRINTER THAT EXPOSES POSITIVE FILM TO THE NEGATIVE FILM. THE POSITIVES MAY BE VIEWED AND INTERCOMPARED ON A MERGING COMPARATOR, OR DIGITIZED FOR COMPUTERIZED IMAGE ANALYSIS. INCORPORATED INTO THE PRINTING SYSTEM IS A UNIQUE TECHNIQUE FOR REMOVING DENSE BACKGROUND AREAS SUCH ASMAY EXIST IN SILVER-STAINED GELS. THE SYSTEM IS FLEXIBLE RETAINS THE ORIGINAL IMAGE FOR STUDY OR REPRODUCTION. ONE CENTRALIZED DIGITIZING SCANNER CAN SERVE NUMEROUS REMOTE 70-MM GEL CAMERAS.

Principal Investigator:

Norman Gulack Anderson
Principal Investigator
3018812600

Business Contact:

Small Business Information at Submission:

Large Scale Biology Corp.
7503 Standish Pl Rockville, MD 20855

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No