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IT IS LAWRENCE MEDICAL SYSTEMS' HYPOTHESIS THAT NONINVASIVE DETERMINATION OF…

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
4987
Program Year/Program:
1986 / SBIR
Agency Tracking Number:
4987
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Lawrence Medical Systems Inc
14910 Northeast 31st Circl Redmond, WA 98052
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1986
Title: IT IS LAWRENCE MEDICAL SYSTEMS' HYPOTHESIS THAT NONINVASIVE DETERMINATION OF CARDIAC OUTPUT WILL IDENTIFY THE PATHOPHY- SIOLOGIC BASIS OF A PATIENT'S HYPERTENSION.
Agency: HHS
Contract: N/A
Award Amount: $50,000.00
 

Abstract:

IT IS LAWRENCE MEDICAL SYSTEMS' HYPOTHESIS THAT NONINVASIVE DETERMINATION OF CARDIAC OUTPUT WILL IDENTIFY THE PATHOPHY- SIOLOGIC BASIS OF A PATIENT'S HYPERTENSION. THAT IS, WHETHER THE HYPERTENSION IS DUE TO ELEVATED CARDIAC OUTPUT, INCREASED SYSTEMIC VASCULAR RESISTANCE, OR BOTH. THIS KNOWLEDGE WILL BE USEFUL IN SELECTING THE BEST ANTIHYPER- TENSIVE REGIMEN FOR INDIVIDUAL PATIENTS, RESULTING IN BETTERBLOOD PRESSURE CONTROL, FEWER MEDICATIONS, FEWER ADVERSE SIDE EFFECTS, AND BETTER PRESCRIPTION COMPLIANCE. IN ORDER TO DEVELOP MARKET POTENTIAL, INNOVATION IS REQUIRED IN TWO AREAS: (1) THE EASE OF USE OF NONINVASIVE CARDIAC OUTPUT MEASUREMENT MUST BE ENHANCED TO MATCH THE EXPECTED OPERATOR SKILL LEVELS FOUND IN THE OUTPATIENT TREATMENT SETTING. (2)HYPERTENSION TREATMENT PRACTICES MUST BE CHANGED FROM THE ACCEPTED "STEPPED CARE" DRUG THERAPY PROTOCOLS TO ONE THAT SELECTS THE BEST DRUG TREATMENT REGIMEN BASED ON EACH PATIENT'S HEMODYNAMIC PATTERN. IN PHASE I, LAWRENCE'S CURRENT CONTINUOUS CARDIAC OUTPUT MEASUREMENT SYSTEM WILL BEMODIFIED AND ITS ACCURACY WILL BE VERIFIED FOR USE IN THE PHYSICIAN'S OFFICE. PHASE II WILL BE A MULTI-CENTER STUDY OF THE BENEFITS OF HEMODYNAMIC-BASED, CONTROLLED DRUG THERAPY FOR HYPERTENSION.

Principal Investigator:

Stephen r barnes
PRINCIPAL INVESTIGATOR
5098855093

Business Contact:

Small Business Information at Submission:

Lawrence Medical Systems Inc
14910 Northeast 31st Circl Redmond, WA 98052

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No