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A RELIABLE TEST FOR GASTROINTESTINAL LESIONS

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
2990
Program Year/Program:
1987 / SBIR
Agency Tracking Number:
2990
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
LITMUS CONCEPTS, INC.
2981 COPPER RD SANTA CLARA, CA 95051
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 2
Fiscal Year: 1987
Title: A RELIABLE TEST FOR GASTROINTESTINAL LESIONS
Agency: HHS
Contract: N/A
Award Amount: $264,000.00
 

Abstract:

FECAL OCCULT BLOOD TESTS (FOBT) ARE COMMONLY USED TO DETECT BLOOD RELEASED FROM GI LESIONS. FOR EXAMPLE, COLORECTAL CANCER IS THE MOST COMMON SERIOUS CANCER IN THE U.S. (100,000 NEW CASES AND 50,000 DEATHS ANNUALLY). BECAUSE IT IS RELATIVELY SLOWLY PROGRESSIVE WITH A LONG ASYMPTOMATIC PERIOD, COLORECTAL CANCER PROVIDES AN IDEAL OPPORTUNITY FOR EARLY DETECTION AND SUCCESSFUL THERAPY. SINCE COLORECTAL CANCERS AND PRECARIOUS LESIONS FREQUENTLY BLEED, FOBT ARE A RATIONAL ATTEMPT AT EARLY DETECTION. SIMILARLY, HOSPITALS AND PHYSICIANS FREQUENTLY UTILIZE FOBT TO DETECT AND MONITOR GI LESIONS NUMEROUS CLINICAL STUDIES ILLUSTRATE THAT CURRENT FOBT SUFFER FROM SERIOUS LIMITATIONS IN SENSITIVITY AND SPECIFICITY. UNFORTUNATELY PROPOSED ALTERNATIVES ARE NO LONGER SIMPLE, RAPID, COST-EFFECTIVE, ON-SITE THIS PROJECT WILL SHOW THE FEASIBILITY OF UPDATING CURRENT FOBT TECHNOLOGY TO IMPROVE CLINICAL PERFORMANCE WHILE RETAINING KEY USER ADVANTAGES.

Principal Investigator:

Paul J. Lawrence
Principal Investigator
4083796309

Business Contact:

Small Business Information at Submission:

Litmus Concepts Inc.
2082 Abbey Lane Campbell, CA 95008

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No