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Company Information:

Company Name: LKT LABORATORIES, INC.
City: ST. PAUL
State: MN
Zip+4: 55114
Woman-Owned: No
Minority-Owned: Yes
HUBZone-Owned: No
Website URL: N/A
Phone: (651) 644-8424

Award Totals:

Program/Phase Award Amount ($) Number of Awards
SBIR Phase I $731,000.00 12
SBIR Phase II $1,744,539.00 3

Award List:

NATURAL CHEMOPREVENTIVE AGENTS

Award Year / Program / Phase: 1988 / SBIR / Phase I
Agency: HHS
Principal Investigator:
Award Amount: $50,000.00

NATURAL CHEMOPREVENTIVE AGENTS

Award Year / Program / Phase: 1990 / SBIR / Phase II
Agency: HHS
Principal Investigator:
Award Amount: $494,538.00
Abstract:
The overall objective of this research program is to test and discover anticarcinogens in essential oils and by-products of food flavorings. essential oils and by-products will be tested for their ability to elicit increased activity of the detoxifying enzyme system, glutathione s-transferase, in… More

PROINHIBITORS OF CHEMICAL CARCINOGENESIS

Award Year / Program / Phase: 1991 / SBIR / Phase I
Agency: HHS
Principal Investigator: Lam, Luke K T , Principal Investigator
Award Amount: $50,000.00
Abstract:
The overall objective of this research project is to study chemopreventive agents that are designed to reach the large bowel and prevent colon cancer. a total of eight compounds that are derivatives of known inhibitors of chemical carcinogenesis will be synthesized. the ability of these… More

RAPID SCREENING OF INHIBITORS OF COLON CARCINOGENESIS

Award Year / Program / Phase: 1991 / SBIR / Phase I
Agency: HHS
Principal Investigator: Lam, Luke K , Principal Investigator
Award Amount: $50,000.00
Abstract:
The mortality rate due to colorectal cancer is second only to lung cancer. one of the strategies to reduce human cancer is by chemoprevention. while there are a number of chemical compounds that show great promise as potential chemopreventive agents, more specific inhibitors of colon carcinogenesis… More

BYPASS COLOSTOMY MODEL FOR CARCINOGENESIS STUDIES

Award Year / Program / Phase: 1991 / SBIR / Phase I
Agency: HHS
Principal Investigator: Zhang, Jilun , Principal Investigator
Award Amount: $50,000.00

ISOTHIOCYNATE CONJUGATES AS CANCER CHEMOPREVENTIVES

Award Year / Program / Phase: 1992 / SBIR / Phase I
Agency: HHS
Principal Investigator: Guo Qiang Zheng
Award Amount: $50,000.00
Abstract:
The objective of this project is to develop a series of water soluble conjugates os isothiocyanates as a novel type of prodrug with site specificity and less toxicity against bladder and colon cancer. the approach to the design of prodrugs is based on the observation that when isothiocyanates were… More

BYPASS COLOSTOMY MODEL FOR CARCINOGENESIS STUDIES

Award Year / Program / Phase: 1993 / SBIR / Phase II
Agency: HHS
Principal Investigator: Zhang, Jilun , Principal Investigator
Award Amount: $500,000.00
Abstract:
The objectives of this research are to study the mechanism of carcinogenesis and chemoprevention of colorectal cancer. human colorectal cancer is a major problem in the united states and is second only to lung cancer as a cause of death. a surgical bypass colostomy model to study colorectal… More

Glutathione Generators in Cancer Chemoprevention

Award Year / Program / Phase: 1993 / SBIR / Phase I
Agency: HHS
Principal Investigator: Luke K. Lam
Award Amount: $50,000.00
Abstract:
The objective of this research is to design and synthesize certain compounds that will stimulate the biosynthesis of glutathione (GSH). We will also evaluate the potential of the compounds as adjuvant chemopreven- tive agents when used alone and in combination with glutathione S-transferase (GST)… More

Anticarcinogenic Constituents from Ganoderma Lucidum

Award Year / Program / Phase: 1993 / SBIR / Phase I
Agency: HHS
Principal Investigator: Luke Lam
Award Amount: $50,000.00
Abstract:
The objective is to isolate and characterize anticarcinogenic constituents from the fungus plant Ganoderma lucidum using bioassay-directed fractionation. The approach to the discovery of potential chemopreventive agents is based on the observation that the chemical components in G. lucidum were… More

Stable Derivatives of Fecapentaene

Award Year / Program / Phase: 1993 / SBIR / Phase I
Agency: HHS
Principal Investigator: Luke K T. Lam
Award Amount: $50,000.00
Abstract:
The objectives are to synthesize stable derivatives of the human fecal mutagen, fecapentaene, and study their effects as colon carcinogens. In this Phase I study, four derivatives of fecapentaene-12 will be synthesized. The partition coefficients of these derivatives, which measure the lipophilicity… More

Water-Soluble Prodrugs of Taxol Against Colon Cancer

Award Year / Program / Phase: 1993 / SBIR / Phase I
Agency: HHS
Principal Investigator: Luke K T. Lam
Award Amount: $50,000.00
Abstract:
The objective is the development of taxol prodrugs targeted for the treatment of colon cancer. Mortality due to colorectal cancer is second only to lung cancer and is estimated to cause 58,300 deaths a year. New case estimates are higher and are more than double for 1992. Site specific drug delivery… More

Cancer Chemoprevention by Sulfur Compounds

Award Year / Program / Phase: 1994 / SBIR / Phase I
Agency: HHS
Principal Investigator: Luke Lam
Award Amount: $81,000.00

Cancer Chemoprevention by Sulfur Compounds

Award Year / Program / Phase: 1996 / SBIR / Phase II
Agency: HHS
Principal Investigator: Luke Lam
Award Amount: $750,001.00
Abstract:
Our objectives are to design and synthesize sulfur containing compounds that stimulatedetoxifying enzymes as defenses against carcinogens. We will develop these compounds into cancerchemopreventive agents for human use. To test the feasibility of the new compounds as potentialinhibitors of… More

PROINHIBITORS OF COLON CARCINOGENESIS

Award Year / Program / Phase: 1997 / SBIR / Phase I
Agency: HHS
Principal Investigator: Lam, luke k
Award Amount: $100,000.00

BIFUNCTIONAL ORGANOSELENIUM COMPOUNDS IN CHEMOPREVENTION

Award Year / Program / Phase: 1999 / SBIR / Phase I
Agency: HHS
Principal Investigator: Nayaz Ahmed
Award Amount: $100,000.00
Abstract:
Not Available The increasing momentum of interconnected distributed systems is revolutionizing notions of interoperability. Open standards and simple, scalable approaches to distributing data and applications have resulted in the explosive acceptance of the World Wide Web (WWW), the Java… More