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Nanoparticles and Nanocapsules for Glioma Targeting

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
88960
Program Year/Program:
2008 / SBIR
Agency Tracking Number:
CA135906
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
LNKCHEMSOLUTIONS
4701 INNOVATION DRIVE LINCOLN, NE -
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2008
Title: Nanoparticles and Nanocapsules for Glioma Targeting
Agency: HHS
Contract: 1R43CA135906-01
Award Amount: $400,001.00
 

Abstract:

DESCRIPTION (provided by applicant): LNK Chemsolutions LLC collaborates with researchers from the University of Chicago to develop nanocapsule technology for enhanced delivery to gliomas. Preliminary results are particularly encouraging in that the nanocap sules display very good transport in healthy rat brains, and they can easily be designed for targeted delivery and timed payload release. In vitro and in vivo models aimed at determining the ability of these nanocapsules to penetrate the blood brain barrie r and to treat induced tumors are envisioned. A variety of imaging techniques and nanocapsule characterization methods have already been tested by the team with very good success. From a commercial standpoint, the technology platform is general and flexibl e, and will allow the company to develop a drug delivery platform product line in the long term. Public Health Relevance: A novel strategy to design nanoparticles and nanocapsules that enhance targeting of gliomas is described. The multi-pronged app roach involves scientists from the medical, chemistry and chemical engineering fields. From a commercial standpoint, ease of fabrication and encapsulation yields are viewed as key competitive traits of the technology in this proposal compared to alternativ e methods.

Principal Investigator:

Business Contact:


LNKChemsolutions@netscape.net
Small Business Information at Submission:

LNKCHEMSOLUTIONS
2411 WINCHESTER SOUTH LINCOLN, NE 68512

EIN/Tax ID: 470833036
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No