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COLOR BASED AUTOMATED MICRONUCLEI ASSAY
- Small Business Information
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Woman-Owned: YesMinority-Owned: NoHUBZone-Owned: No
- Phase 2
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Fiscal Year: 1993Title: COLOR BASED AUTOMATED MICRONUCLEI ASSAYAgency: HHSContract: N/AAward Amount: $500,000.00
Abstract:
THIS PROJECT IS FOR THE DEVELOPMENT OF AN AUTOMATED COLOR BASED MICRONUCLEI ASSAY SYSTEM BASED ON RESULTS OF A PROTOTYPE MS-DOS COLOR ANALYSIS SYSTEM. THE SYSTEM WILL AUTOMATICALLY LOCATE AND COUNT POLYCHROMATIC ERYTHROCYTES (PCE'S), MICRONUCLEATED POLYCHROMATIC ERYTHROCYTES (MPCES) AND NORMOCHROMATIC ERYTHROCYTES (NCES). DURING PHASE I, A NUMBER OF CRITICAL VARIABLE PARAMETERS PREVIOUSLY DEVELOPED WILL BE ADAPTED INTO A USER-FRIENDLY INTERACTIVE PROGRAM CAPABLE OF RAPIDLY SELECTING THE APPROPRIATE PARAMETERS FOR EACH NEW SLIDE PREPARATION. THESE PARAMETERS INCLUDE: THE LEVEL OF BACKGROUND STRAIN; CRITERIA FOR ACCEPTABLE ERYTHROCYTE SIZE RANGE AND ROUNDNESS; AND COLOR DISCRIMINATION. COLOR DISCRIMINATION IS THE KEY ELEMENT FOR DIFFERENTIATION. THE SYSTEM WILL BE IMPLEMENTED ON A MACINTOSH IIFX COMPUTER. IT WILL INCLUDE A CAPABILITY TO AUTOMATICALLY PROCESS MULTIPLE SLIDES AND PRODUCE AUTOMATIC REPORTS INCLUDING APPROPRIATE STATISTICAL ANALYSIS. BY CAPTURING ALL IMAGES WITH SCORED MICRONUCLEI THE SYSTEM PROVIDES A NECESSARY AUDIT TRAIL FOR REGULATORY OVERVIEW.Small Business Information at Submission:Principal Investigator:
Loats, Harry L
Principal Investigator
4108768055Business Contact:
1 r43 es05872-01Loats Associates, Inc.
1004 Littlestown Pike Westminster, MD 21157EIN/Tax ID: 521241956DUNS: N/ANumber of Employees: N/AWoman-Owned: NoMinority-Owned: NoHUBZone-Owned: No
Award Information
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Agency: Department of Health and Human Services |
Branch: N/A |
Award ID: 16578 |
Program Year/Program: 1993 / SBIR |
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Agency Tracking Number: 16578 |
Solicitation Year: N/A |
Solicitation Topic Code: N/A |
Solicitation Number: N/A |