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Novel Instrumentation for Nitric Oxide Measurements in Biological Samples

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
89183
Program Year/Program:
2008 / SBIR
Agency Tracking Number:
GM083491
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
LOS GATOS RESEARCH
67 E EVELYN AVE STE3 Mountain View, CA 94041-1529
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2008
Title: Novel Instrumentation for Nitric Oxide Measurements in Biological Samples
Agency: HHS
Contract: 1R43GM083491-01
Award Amount: $99,358.00
 

Abstract:

DESCRIPTION (provided by applicant): In this Small Business Innovative Research Phase I project, Los Gatos Research (LGR) proposes to develop and test a novel mid-infrared laser-based NO Analyzer for measurements of nitric oxide concentration in cellular m edia (biological samples) over a wide dynamic range (from picomole to micromole) and with a high sensitivity (picomole). The instrument will be based on LGR's patented Off-Axis ICOS technology. In this Phase I effort, LGR is collaborating with the Universi ty of Alabama Huntsville (UAH) to develop and deploy and test this novel portable instrument. System performance will be demonstrated first in gravimetrically prepared gas samples at LGR and subsequently in aqueous biological samples at UAH. The results wi ll be validated by direct comparison with conventional chemiluminescence analyzers (at LGR) and electrochemical probes (at UAH).

Principal Investigator:

Business Contact:

Small Business Information at Submission:

LOS GATOS RESEARCH
LOS GATOS RESEARCH 67 E EVELYN AVE, STE 3 MOUNTAIN VIEW, CA 94041

EIN/Tax ID: 770358688
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No