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OMEGA-3 POLYUNSATURATED FATTY ACIDS FROM ALGAE

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
7333
Program Year/Program:
1988 / SBIR
Agency Tracking Number:
7333
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
MARTEK BIOSCIENCE CORPORATION
6480 DOBBIN RD COLUMBIA, MD 21045
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 2
Fiscal Year: 1988
Title: OMEGA-3 POLYUNSATURATED FATTY ACIDS FROM ALGAE
Agency: HHS
Contract: N/A
Award Amount: $473,000.00
 

Abstract:

RECENT INVESTIGATIONS INDICATE A SIGNIFICANT CORRELATION BETWEEN DIETARY SUPPLEMENTS OF POLYUNSATURATED FATTY ACIDS (PUFA), ESPECIALLY OMEGA-3 PUFAS, AND REDUCED INCIDENCE OF CORONARY HEART DISEASE. CLINICAL INTERESTS HAVE FOCUSED ON POTENTIAL USAGE OF OMEGA-3 PUFAS, IN THE TREATMENT OF HYPERCHOLESTEREMIA AND HYPERTRIGLYCERIDEMIA. AT PRESENT, THE ONLY SOURCE OF OMEGA-3 PUFAS IS OIL FROM CERTAIN MARINE FISHES. HOWEVER, MANY SPECIES OF ALGAE ALSO PRODUCE LARGE AMOUNTS OF OMEGA-3 PUFAS AND MARTEK CORPORATION BELIEVES THAT THIS GROUP OF ORGANISMS COULD PROVIDE AN INVALUABLE SUPPLY SOURCE OF OMEGA-3 PUFAS FOR CLINICAL TRIALS AND/OR FOOD ADDITIVE TESTING USING ALGAL MONOCULTURE. PHASE I WILLINVOLVE (1) ESTABLISHING SEVERAL OMEGA-3 PUFA-PRODUCING ALGAL SPECIES IN CULTURE; (2) OPTIMIZING THE GROWTH CONDITIONS AND DETERMINING THE MAXIMUM OMEGA-3 PUFA PRODUCTIVITIES; AND (3) EXTRACTING AND PURIFYING THE OMEGA-3 PUFA'S IN PREPARATIVE QUANTITIES. IF SIGNIFICANT ADVANTAGES OVER THE FISH OIL SOURCE ARE IDENTIFIED, PHASE II WILL INVOLVE SCALE-UP PRODUCTION AND ANEFFORT TARGETED TO INCREASE SPECIFIC OMEGA-3 PUFA OUTPUTS FROM ALGAL SOURCES BY STRAIN IMPROVEMENT AND GENETIC MODIFICATION.

Principal Investigator:

David J Kyle Phd
3014902566

Business Contact:

Small Business Information at Submission:

Martek Corp.
9115 Guilford Road Columbia, MD 21046

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No