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INEXPENSIVE PRODUCTION OF UNIVERSALLY LABELLED CARBON-13 BIOMOLECULES BY ALGAE

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
8147
Program Year/Program:
1990 / SBIR
Agency Tracking Number:
8147
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
MARTEK BIOSCIENCE CORPORATION
6480 DOBBIN RD COLUMBIA, MD 21045
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 2
Fiscal Year: 1990
Title: INEXPENSIVE PRODUCTION OF UNIVERSALLY LABELLED CARBON-13 BIOMOLECULES BY ALGAE
Agency: HHS
Contract: N/A
Award Amount: $277,130.00
 

Abstract:

STABLE ISOTOPES ARE WIDELY USED IN DIAGNOSIS OF DISEASES ANDDISORDERS IN GASTRO-ENTEROLOGY. THEY ALSO FIND APPLICATION AS TRACERS FOR METABOLIC STUDIES. THEY ARE NON-INVASIVE AND NON-TOXIC. ALGAE FIX CO(2) AND CAN THEREFORE INCORPORATE (13)CO(2) INTO BIOMOLECULES THAT CAN BE USED AS ISOTOPIC TRACERS. ALGAL PRODUCTION OF (13)C-LABELLED TRIOLEIN, GLUCOSE AND XYLOSE WILL BE STUDIED. THESE COMPOUNDS ARE WIDELY USED IN MEDICAL DIAGNOSTICS, AND CAN BEPRODUCED IN LARGE AMOUNTS BY A SINGLE ALGAL SPECIES. IN PHASE I WE WILL GROW THE ORGANISM, ISOLATE AND PURIFY GLUCOSE, XYLOSE AND TRIOLEIN AND DETERMINE THE PRODUCTION ECONOMICS. THIS WORK WILL SHOW (A) THAT STABLE ISOTOPES CAN BE PREPARED FROM ALGAE AND (B) THAT THE COST OF PRODUCTION FROM ALGAE IS SIGNIFICANTLY CHEAPER THAN CHEMICAL ALTERNATIVES.

Principal Investigator:


0

Business Contact:

Small Business Information at Submission:

Martek Corp.
6480 Dobbin Rd Columbia, MD 21045

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No