USA flag logo/image

An Official Website of the United States Government

Novel Magnetic Homeostatic Agents to Arrest Hemorrhage

Award Information

Agency:
Department of Defense
Branch:
Defense Advanced Research Projects Agency
Award ID:
58470
Program Year/Program:
2004 / SBIR
Agency Tracking Number:
02SB2-0477
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Materials Modification Inc
2809-K Merrilee Drive Fairfax, VA -
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 2
Fiscal Year: 2004
Title: Novel Magnetic Homeostatic Agents to Arrest Hemorrhage
Agency / Branch: DOD / DARPA
Contract: W31P4Q-04-C-R036
Award Amount: $750,000.00
 

Abstract:

The Phase II SBIR project aims at developing novel approaches for controlling the so-called "non-compressible hemorrhage." The approach would involve formulating a biocompatible magnetic fluid, which would undergo a reversible liquid-solid transition at the site of injury and seal off the broken blood vessel. This would improve the immediate management in the field of combat casualties with minor to moderate bleeding. Our initial goal is to develop means for controlling bleeding from sites located on the extremities and/or from lacerations involving the femoral or axillary vessels. During the Phase I effort, we successfully formulated magnetic nanoparticles which were non-toxic to human cell lines and have an appreciable magnetic moment and a superparamagnetic nature. Phase II will focus on long term in vitro as well as in vivo toxicity in both small and large animals followed by testing in small and large animal bleeding models.

Principal Investigator:

Sanjay Kotha
Team Leader
7035601371
skotha@matmod.com

Business Contact:

T. Sudarshan
President & CEO
7035601371
sudarshan@matmod.com
Small Business Information at Submission:

MATERIALS MODIFICATION, INC.
2721-D Merrilee Drive Fairfax, VA 22031

EIN/Tax ID: 541368539
DUNS: N/A
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No