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Company Information:

Company Name: Mb Research Laboratories, Inc.
City: SPINNERSTOWN
State: PA
Zip+4: 18968-
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Website URL: N/A
Phone: (215) 536-4110

Award Totals:

Program/Phase Award Amount ($) Number of Awards
SBIR Phase I $897,137.00 9
SBIR Phase II $3,572,989.00 3

Award List:

N/A

Award Year / Program / Phase: 2000 / SBIR / Phase I
Agency: HHS
Principal Investigator: George L. Degeorge
Award Amount: $99,999.00

N/A

Award Year / Program / Phase: 2000 / SBIR / Phase I
Agency: HHS
Principal Investigator: George L. Degeorge
Award Amount: $99,842.00

N/A

Award Year / Program / Phase: 2000 / SBIR / Phase I
Agency: HHS
Principal Investigator: Edward J. Yurkow
Award Amount: $100,000.00

Alternative Photosensitization Assay in the Mouse

Award Year / Program / Phase: 2001 / SBIR / Phase I
Agency: HHS
Principal Investigator: George L. Degeorge
Award Amount: $99,999.00
Abstract:
DESCRIPTION (provided by applicant): This proposal, "Alternative Photosensitization Assay in the Mouse (Photo-LLNA)," is an alternative animal test designed to identify substances with immunotoxic properties. There has evolved an… More

Phototoxicity using the Chorioallantoic Membrane

Award Year / Program / Phase: 2001 / SBIR / Phase I
Agency: HHS
Principal Investigator: Daniel R. Cerven
Award Amount: $100,000.00
Abstract:
DESCRIPTION (Applicant's Abstract): This proposal, "Phototoxicity Screen using the Chorioallantoic Membrane" (PhotoCAM) is an alternative phototoxicity screening test to identify chemical mediators and substances with phototoxic properties, which is in demand by the… More

FLOW (CYTOMETRY)-BASED UNSCHEDULED DNA SYNTHESIS ASSAY

Award Year / Program / Phase: 2001 / SBIR / Phase I
Agency: HHS
Principal Investigator: Edward J. Yurkow
Award Amount: $99,998.00
Abstract:
DESCRIPTION: The development of an improved assay for genotoxicity is proposed. The assay will be based on the Unschedule DNA Synthesis assay that measures nucleotide incorporation due to repair of DNA damage. The proposal seeks to modify the assay to use non-radioactive… More

ENHANCED LOCAL LYMPH NODE ASSAY USING FLOW CYTOMETRY

Award Year / Program / Phase: 2002 / SBIR / Phase I
Agency: HHS
Principal Investigator: George L. Degeorge
Award Amount: $0.00
Abstract:
DESCRIPTION (Applicant?s abstract): Although the murine Local Lymph Node Assay (LLNA) is effective at detecting potential irritants/sensitizers, this assay, in its current standard form: 1) cannot readily differentiate some types of irritants from respiratory and contact sensitizers; 2) utilizes… More

ENHANCED LOCAL LYMPH NODE ASSAY USING FLOW CYTOMETRY

Award Year / Program / Phase: 2002 / SBIR / Phase II
Agency: HHS
Principal Investigator: George L. Degeorge
Award Amount: $1,142,638.00
Abstract:
DESCRIPTION (Applicant?s abstract): Although the murine Local Lymph Node Assay (LLNA) is effective at detecting potential irritants/sensitizers, this assay, in its current standard form: 1) cannot readily differentiate some types of irritants from respiratory and contact sensitizers; 2) utilizes… More

ENHANCED PHOTOTOXICITY ASSAY IN RECONSTITUTED SKIN

Award Year / Program / Phase: 2002 / SBIR / Phase I
Agency: HHS
Principal Investigator: George L. Degeorge
Award Amount: $188,703.00
Abstract:
DESCRIPTION (provided by applicant): We have conceived a high-throughput in vitro screening test for Phototoxicity designated the "Enhanced Phototoxicity Assay in Reconstituted Skin (EPARS). The phototoxic potential of chemicals, cosmetics, dietary supplements and pharmaceuticals are a growing… More

Flow cytometry-based Unscheduled DNA Synthesis (FLUDS)

Award Year / Program / Phase: 2004 / SBIR / Phase II
Agency: HHS
Principal Investigator: George L. Degeorge
Award Amount: $1,075,152.00
Abstract:
DESCRIPTION (provided by applicant): There is a growing need in industry for an inexpensive screening assay which can reliably determine the genotoxic potential of the large number of new chemical compounds synthesized each year. The Unscheduled DNA Synthesis (UDS) Assay is a proven method to… More

Phototoxicity Screening Assay in Reconstituted Skin

Award Year / Program / Phase: 2005 / SBIR / Phase II
Agency: HHS
Principal Investigator: George Degeorge
Award Amount: $1,355,199.00
Abstract:
DESCRIPTION (provided by applicant): We have developed and prevalidated an in vitro screening test for phototoxicity, the Enhanced Phototoxicity Assay in Reconstituted Skin (EPARS), to replace the current standard animal phototoxicity tests. The phototoxic potential of chemicals, cosmetics, dietary… More

Novel Use of Confocal Microscopy on Cultured Porcine Corneas for Pre-Clinical Tes

Award Year / Program / Phase: 2011 / SBIR / Phase I
Agency: HHS
Principal Investigator: Michelle Piehl – 215-536-4110
Award Amount: $108,596.00
Abstract:
DESCRIPTION (provided by applicant): There is an important need for screening methods that can detect and distinguish the relative eye discomfort or sting potential of cosmetic, personal care, or pharmaceutical formulations early in their developmental stages. The only currently reliable method… More