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Totally Implantable Artificial Lung

Award Information

Department of Health and Human Services
Award ID:
Program Year/Program:
1997 / SBIR
Agency Tracking Number:
Solicitation Year:
Solicitation Topic Code:
Solicitation Number:
Small Business Information
Michigan Critical Care Consultants, Inc.
3550 West Liberty Suite 3 Ann Arbor, MI -
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Phase 2
Fiscal Year: 1997
Title: Totally Implantable Artificial Lung
Agency: HHS
Contract: 1 R43 HL53168-01A1,
Award Amount: $741,500.00


A totally implantable intrapleural artificial lung (AL) is presented. The AL is designed to fully spatients who require long term (more than one month) artificial gas exchange support necessary for tThe device will also provide a bridge to lung transplantation when lung recovery is impossible. Theperfused entirely by the right ventricle while the device is placed in series or in parallel with thpulmonary artery (PA) to PA, or PA to left atrium. MC3 has prototyped several extremely low resistanartificial lungs, and in collaboration with the University of Michigan, has successfully implanted tacute sheep experiments. In these experiments the AL was capable of fully supporting adult sheep whidrop across the device was tolerable by the right ventricle. Our objective in Phase I will be to furand to fully characterize the hemodynamics and gas exchange of devices that are made from silicone mmicroporous hollow fibers. This characterization will be helpful in determining how the various desiresistance to blood flow and gas exchange. Based on these results we will improve the design to advaat long term use.

Principal Investigator:

Jean Montoya

Business Contact:

Small Business Information at Submission:

Michigan Critical Care
245 Jackson Industrial Drive, Ann Arbor, MI 48103

Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No