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NOVEL DENSE HOLLOW FIBER FOR BLOOD-GAS EXCHANGE

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
60242
Program Year/Program:
2002 / SBIR
Agency Tracking Number:
HL068375
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
MEDARRAY, INC.
2875 WALTERS WAY ANN ARBOR, MI -
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2002
Title: NOVEL DENSE HOLLOW FIBER FOR BLOOD-GAS EXCHANGE
Agency: HHS
Contract: 1R43HL068375-01A1
Award Amount: $160,699.00
 

Abstract:

We have devised a technique that will greatly simplify and make cost effective the fabrication of dense silicone fibers for use in gas exchange applications including long-term extracorporeal life support, implantable artificial lung, and other cardiorespiratory procedures. The technique allows for producing, non-porous, high performing, and economically attractive compact gas exchange devices, analogous to their microporous membrane hollow fibers (MMHF) counterparts. Devices incorporating MMHF have become popular mainly because of enhanced gas exchange due to the convective mixing induced by blood flowing over thousands of tiny hollow fibers. This property allows for designing highly efficient gas exchange devices in relatively compact volumes. Yet MMHF suffer from fowling, and plasma leakage when they are used for extended periods of time, and from propensity to gas embolization when the gas side pressure exceeds the blood side pressure. Thus incorporating the compactness and effectiveness of hollow fibers configuration with the ability of solid silicone membranes to withstanding plasma leakage and gas embolization are desirable properties in a membrane designed blood oxygenation. In Phase 1 we propose to further develop the fabrication technique and to evaluate the gas exchange and hemodynamic performance of the dense hollow fibers incorporated in prototype as exchange devices.

Principal Investigator:

Jean P. Montoya
7347613889
MONTOYA@MEDARRAY.COM

Business Contact:

Jean Montoya
7347613889
MAIN@MEDARRAY.COM
Small Business Information at Submission:

MEDARRAY, INC.
MEDARRAY, INC. 1610 HARBAL DR ANN ARBOR, MI 48105

EIN/Tax ID: 383537892
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No