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MULTIPLY-TUNED MRS, LOCAL GRADIENT HEAD COIL

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
19461
Program Year/Program:
1992 / SBIR
Agency Tracking Number:
19461
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Medical Advances, Inc.
10437 Innovation Drive Milwaukee, WI 53226
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1992
Title: MULTIPLY-TUNED MRS, LOCAL GRADIENT HEAD COIL
Agency: HHS
Contract: N/A
Award Amount: $50,000.00
 

Abstract:

THE OBJECTIVE IS TO DEVELOP A VOLUME COIL FOR MULTI-FREQUENCY MR SPECTROSCOPY OF THE HUMAN BRAIN. THIS DEVELOPMENT IS EXPECTED TO SUBSTANTIALLY AID CLINICAL SPECTROSCOPIC RESEARCH IN PROVIDING A NON-INVASIVE METHOD OF MONITORING BIOCHEMISTRY AND PHYSIOLOGY IN A LESION. SIGNIFICANT IMPROVEMENTS ARE EXPECTED IN SENSITIVITY, UNIFORMITY, AND APPLICATION FEATURES OVER EXISTING COMMERCIAL PRODUCTS. THESE FEATURES ARE: MULTIPLE TUNING TO FACILITATE PROTON IMAGINING AS WELL AS COLLECTION OF HYDROGEN, PHOSPHOROUS, AND FLURINE SPECTRA; QUADRATURE DETECTION BIRDCAGE DESIGN TO ENHANCE SIGNAL-TO-NOISE (S/N) AND INIFORMITY; CUT-OUTS TO FACILITATE PATIENT POSITIONING AND REDUCE CLAUSTROPHOBIA-INDUCED ANXIETY; AND FARADAY SCREENING TO ACCOMMODATE COMBINATION WITH LOCAL GRADIENT COILS. A THREE-AXIS LOCAL GRADIENT COIL WILL BE DESIGNED (IN PHASE I) CONCENTRIC WITH THE MULTI-TUNED BIRDCAGE COIL. LOCAL GRADIENT COILS IMPROVE THE TEMPORAL RESOLUTION AND ACCOMADATE SHORTER ECHO TIMES IN THE DATA ACQUISITION PHASE, THEREBY IMPROVING THE SELECTIVITY OF THE VOLUME-OF-INTEREST AND INCREASING THE NUMBER OF CONTRACT ENHANCEMENT PROTOCOLS (RESPECTIVELY). THESE EFFORTS WILL LEAD DIRECTLY INTO THE PHASE II IMPLEMENTATION AND DEVELOPMENT OF A THREE-AXIS LOCAL GRADIENT COIL COMBINED WITH THE MULTI-FREQUENCY SPECTROSCOPY HEAD COIL.

Principal Investigator:

Randall W Jones
4142583808

Business Contact:

Small Business Information at Submission:

Medical Advances Inc
Po Box 26425 Milwaukee, WI 53226

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No