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Lyme Disease Vaccine Using Gonococcal Blebs

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
29113
Program Year/Program:
1995 / SBIR
Agency Tracking Number:
29113
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
MEDIMMUNE, INC.
35 WEST WATKINS MILL RD Gaithersburg, MD 20878
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1995
Title: Lyme Disease Vaccine Using Gonococcal Blebs
Agency: HHS
Contract: 1 R43 AI37479-01,
Award Amount: $100,000.00
 

Abstract:

The investigators will develop a system in which OspA, an antigen known to induce protective immuneagainst Borrelia burgdorferi, the causative agent of Lyme Disease, is cloned and exported to the outNeisseria gonorrhea, a bacterium that naturally turns over its outer membrane into easily isolated iantigen will be expressed in blebs either as a complete protein or by fusion to another gonococcal cLocalization of the antigen in blebs will be characterized and the blebs used in animal studies to dimmunogenicity of the construct as well as its potential ability to elicit protective immune respons

Principal Investigator:

John Cairns
30117

Business Contact:

Small Business Information at Submission:

Medimmune, Inc.
35 W Watkins Mill Road Gaithersburg, MD 20878

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No