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Company Information:

Company Name: MEDIOMICS, LLC
City: SAINT LOUIS
State: MO
Zip+4: 63124-
Woman-Owned: No
Minority-Owned: Yes
HUBZone-Owned: No
Website URL: N/A
Phone: N/A

Award Totals:

Program/Phase Award Amount ($) Number of Awards
SBIR Phase I $829,075.00 5
SBIR Phase II $3,203,348.00 4
STTR Phase I $229,493.00 2
STTR Phase II $954,812.00 1

Award List:

SBIR/STTR Phase I: DNA binding proteins as biosensors

Award Year / Program / Phase: 2002 / SBIR / Phase I
Agency: NSF
Principal Investigator: Ewa Heyduk
Award Amount: $99,109.00
Abstract:
This Small Business Innovation Research Phase I project will develop a new general platform for preparing biosensors for a large number of target molecules. The target molecules for these biosensors will be the compounds (ligands) which regulate DNA binding activity of sequence-specific DNA binding… More

SBIR Phase II: DNA Binding Proteins as Biosensors

Award Year / Program / Phase: 2004 / SBIR / Phase II
Agency: NSF
Principal Investigator: Ewa Heyduk, PI
Award Amount: $498,375.00
Abstract:
This Small Business Innovation Research (SBIR) Phase II project will complete the development of biosensors for detection of heavy metals and acyl-CoA using sequence-specific DNA binding proteins. The presence of the target molecule will be reported by the biosensor as a change in fluorescence… More

Microarrays for DNA binding proteins

Award Year / Program / Phase: 2006 / STTR / Phase I
Agency: HHS
Research Institution: SAINT LOUIS UNIVERSITY
Principal Investigator: Tomasz Heyduk
Award Amount: $100,000.00
RI Contact: N/A
Abstract:
DESCRIPTION (provided by applicant): Highly multiplexed detection of biological molecules and their activities has been an essential element of modern molecular diagnosis, drug development and research in genomics and proteomics. Well established DNA array methodologies exist which permit highly… More

Rapid homogeneous antibody-based detection of proteins

Award Year / Program / Phase: 2007 / STTR / Phase I
Agency: HHS
Research Institution: SAINT LOUIS UNIVERSITY
Principal Investigator: Tomasz Heyduk
Award Amount: $129,493.00
RI Contact: N/A
Abstract:
DESCRIPTION (provided by applicant): Detection of the presence and the determination of the amount of a specific protein using various techniques utilizing antibodies specific to the target protein are one of the most important tools in biomedical research , medical diagnosis and detection of… More

Rapid homogeneous antibody-based detection of proteins

Award Year / Program / Phase: 2009 / STTR / Phase II
Agency: HHS
Research Institution: SAINT LOUIS UNIVERSITY
Principal Investigator: Tomasz Heyduk
Award Amount: $954,812.00
RI Contact: N/A
Abstract:
DESCRIPTION (provided by applicant): Detection and quantification of proteins in various biological samples is one of the most important and most often utilized assays with applications in research, medical diagnosis, early disease detection and detection of biological threat agents. While many… More

Process Analytic Technologies (PAT) for Biologics

Award Year / Program / Phase: 2010 / SBIR / Phase I
Agency: HHS
Principal Investigator: Ling Tian
Award Amount: $185,116.00
Abstract:
Biologic drugs are therapeutic medicinal products engineered from living cells or proteins. The novel introduction of these products has already had an enormous impact on some medical subfields, including rheumatology, cardiology, oncology, and others. Biologics are, however, very complicated to… More

APTAMER-BASED PINCERS FOR CARDIOVASCULAR BIOMARKERS

Award Year / Program / Phase: 2010 / SBIR / Phase I
Agency: HHS
Principal Investigator: Ling Tian
Award Amount: $97,680.00
Abstract:
Not Available

SBIR TOPIC 294 PHASE 1 - DEVELOPMENT OF GLYCOSYLATION - SPECIFIC RESEARCH

Award Year / Program / Phase: 2011 / SBIR / Phase I
Agency: HHS
Principal Investigator: Ling Tan – 314-997-5918
Award Amount: $148,569.00
Abstract:
Glycosylation changes are a universal feature of malignant transformation and tumor progression. Changes in expression levels of certain glycoproteins and altered glycosylation patterns have been detected in most of the major human cancer types and at different stages of tumor progression. The… More

TAS::75 0849::TAS SBIR TOPIC 304 PHASE I DEVELOPMENT OF BLOOD-BASED METHODS FOR THE DETECTION OF CANCER RECURRENCE IN POST-THERAPY BREAST CANCER PATIENTS

Award Year / Program / Phase: 2011 / SBIR / Phase I
Agency: HHS
Principal Investigator: Ling Tian – 314-997-5918
Award Amount: $298,601.00
Abstract:
According to the American Cancer Society, 192,370 women in the United States will be diagnosed with invasive breast cancer in 2010, leading to 40,170 deaths. Most women with breast cancer undergo surgery to remove the cancerous tissue and then receive additional treatment. Adjuvant therapy does not… More

IGF::OT::IGF OTHER FUNCTIONS - PINCER-BASED IN-PROCESS ANALYZER FOR BIOLOGICS

Award Year / Program / Phase: 2012 / SBIR / Phase II
Agency: HHS
Principal Investigator: Ling Tian – 314-997-5918
Award Amount: $997,251.00
Abstract:
Biologic drugs are therapeutic medicinal products engineered from living cells or proteins. The novel introduction of these products has already had an enormous impact on some medical subfields, including rheumatology, cardiology, oncology, and others. Biologics are, however, very complicated to… More

Pincer Assays for Detecting Early Hepatitis C

Award Year / Program / Phase: 2012 / SBIR / Phase II
Agency: HHS
Principal Investigator: Ling Tian
Award Amount: $737,952.00
Abstract:
Early diagnosis of the hepatitis C virus (HCV) infection is crucial for treatment and prevention. PCR screening and ELISA-based assay are currently used to detect viral RNA and HCV antibodies in patient blood samples. There are, however, no commercially available serological assays which can… More

SBIR PHASE II TOPIC 294, DETECTION OF PROTEIN GLYCOSYLATION; HHSN261201300047C; P

Award Year / Program / Phase: 2013 / SBIR / Phase II
Agency: HHS
Principal Investigator: Margaret Meng – 314-997-5918
Award Amount: $969,770.00
Abstract:
Not Available