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THE OBJECTIVE OF THIS WORK IS DEVELOPMENT OF A LASER DOPPLER CATHETER SYSTEM…

Award Information

Agency:
Department of Health and Human Services 		Branch:
N/A 		Award ID:
3247 		Program Year/Program:
1985 / SBIR
Agency Tracking Number:
3247 		Solicitation Year:
N/A 		Solicitation Topic Code:
N/A 		Solicitation Number:
N/A
Small Business Information
Medpacific Corpon
6701 Sixth Avenue South Seattle, WA 98108
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1985
Title: THE OBJECTIVE OF THIS WORK IS DEVELOPMENT OF A LASER DOPPLER CATHETER SYSTEM (LDCS) FOR THE INVASIVE ASSESSMENT OF VASCULAR FLOW.
Agency: HHS
Contract: N/A
Award Amount: $50,000.00
 

Abstract:

THE OBJECTIVE OF THIS WORK IS DEVELOPMENT OF A LASER DOPPLER CATHETER SYSTEM (LDCS) FOR THE INVASIVE ASSESSMENT OF VASCULAR FLOW. CURRENT NONINVASIVE ASSESSMENTS OF CORONARY FLOW (RADIONUCLIDE IMAGING AND RADIOACTIVE MICROSPHERE DISTRIBUTION) ARE COMPLEX AND EXPENSIVE, WHILE LACKING RESOLUTION AND CLINICAL UTILITY. LDCS WOULD ALLOW ABSOLUTE SUBSELECTIVE ASSESSMENT OF CORONARY FLOW AND STENOSIS IN INDIVIDUAL ARTERIES, AND MEASUREMENTS COULD BE OBTAINED DURING DIAGNOSTIC CARDIAC CATHETERIZATION USING STANDARD TECHNIQUES. THE EXPECTED RESULTS OF THE PHASE I EFFORT WILL BE TO CONSTRUCT A PROTOTYPE CATHETER SYSTEM CAPABLE OF MEASURING VELOCITIES UP TO 2 METERS/SECOND. THE SYSTEM WILL BE CALIBRATED IN A HYDRAULIC TEST LOOP, AND WILL SIGNIFICANCE OF THE WORK: THE LDCS WOULD HAVE WIDESPREAD APPLICATION IN THE PHYSIOLOGIC ASSESSMENT OF CORONARY ARTERY DISEASE. CORONARY ANGIOGRAPHY YIELDS NO PHYSIOLOGIC INFORMATION AND OFTEN UNDERESTIMATES INTERMEDIATE (25% TO 60%) STENOSIS. LASER DOPPLER TECHNIQUES, BY SENSING THE HIGH VELOCITY FLOW REGION IN THE STENOTIC LUMEN, COULD AIM HIGH POWER THERAPEUTIC LASER CATHETERS. PERFORATION RISKS WOULD BE MINIMIZED AND TREATMENT EFFECTS COULD BE MONITORED.

Principal Investigator:

Guy f. bogar
PRINCIPAL INVESTIGATOR
2067639177

Business Contact:

Small Business Information at Submission:

Medpacific Corpon
6701 Sixth Avenue South Seattle, WA 98108

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No