The proposed program for monitoring body temperatue utilizes passive, noninvasive microwave radiometry to measure and monitor core temperature. a microwave radiometer - a sensitive microwave receiver - allows the measurement of natural electromagnetic emission from the body at microwave frequencies.… More

Intravenous, or intra-arterial, administration of liquids such as oncotherapeutic drugs commonly uses a hollow needle or catheter inserted into a superficial artery or vein. however, patient movements may dislodge the needle/catheter from the vein or artery, permitting an accumulation of liquid in… More

Acute or chronic failure of the kidneys results in rapid death unless normal kidney function is replaced by dialysis.dialysis purifies the blood in a selective way, removing toxic substances via a semi-permeable membrane, or filter. hemodialysis employs an artificial extracorporeal membrane which… More

Hypovolemic shock, secondary to traumatic exsanguination, is the most common cause of death in severely injured soliders. treatment of hypovolemic shock and attendant hypothermia is the subject of the study proposed here. to address the problem of hypothermia and its associated coagulopathy and… More

It is estimated that almost 75,000 persons will die each year of acute respiratory insufficiency caused by lung disease. to address this problem, extracorporeal membrane oxygenation (ecmo) is used to provide external pumping and membrane oxygenation to assist the weakened or failing heart. heat… More

The use of a microwave based system with a single antenna and radiometer to detect thermal anomalies in the breast has been investigated in several clinical studies. we are now developing a multiple antenna system, based upon the results of these initial studies, to provide greater resolution and… More

The goal of the program is to develop a device for myocardial ablation using microwave heating. the device, consisting of a microprocessor-controlled solid-state microwave energy source at 915 mhz, can deliver localized heating of tissue to create ablation with a small transducer or antenna. the… More

Accidents involving the introduction of air emboli in the coronary or cerebral circulation paths through cardiotomy or pump oxygenator procedures can result in devastating injury. we will develop a non-invasive mechanism for quickly and accurately detecting the presence of air emboli in the infusion… More

The research is intended to address the problem of extravasation events in the neonatal and pediatric patient population. Extravasations of intravenous fluids in children can have serious consequences when gross extravasations occur. Skin necrosis can occur which may require treatment with skin… More

Cancer of the prostate is the second most lethal cancer in American men, primarily affecting individuals over the age of 50. The number of men at risk for this disease is growing rapidly as the population ages. This research is intended to introduce and evaluate Passive Microwave Radiometry (PMR)… More

This proposal defines the development and evaluation of a dedicated microwave device for rapid, autstandardized fixation of tissue biopsies for histopathological examination. Microwave energy is useddilute aldehyde or salt solutions to produce fixation results that are equal in quality to chemicalto… More

DESCRIPTION (Verbatim from Applicant's Abstract): The long-term objective of this research is to improve breast cancer management by utilizing thermal information as an adjunct to mammography to aid in clinical decisions when confronted with equivocal mammograms. … More

DESCRIPTION (Verbatim from Applicant's Abstract): The long-term objective of this research is to improve breast cancer management by utilizing thermal information as an adjunct to mammography to aid in clinical decisions when confronted with equivocal mammograms. … More

DESCRIPTION (Verbatim from Applicant's Abstract): The long-term objective of this research is to improve breast cancer management by utilizing thermal information as an adjunct to mammography to aid in clinical decisions when confronted with equivocal mammograms. … More

DESCRIPTION (Verbatim from Applicant's Abstract): The long-term objective of this research is to improve breast cancer management by utilizing thermal information as an adjunct to mammography to aid in clinical decisions when confronted with equivocal mammograms. … More

DESCRIPTION (provided by applicant): Hypoxic-ischemic encephalopathy (HIE) represents a serious problem in newborns, occurring in 3-9 of every 1000 term infants, with about half of these HIE babies dying or suffering life-long severe handicaps, such as mental retardation or cerebral palsy. Current… More

DESCRIPTION (provided by applicant): Hypoxic-ischemic encephalopathy (HIE) represents a serious problem in newborns, occurring in 3-9 of every 1,000 term infants, with about half of these HIE babies dying or suffering life-long severe handicaps, such as me ntal retardation or cerebral palsy. Current… More