Four novel processes for the control of volatile organic emissions are proposed for investigation. the first of these is based on scrubbing the volatile organics with an oxidation resistant liquid which is regenerated by aqueous phase oxidation using a strong oxidant. a second process isbased on use… More

A novel process for fixed-bed adsorption using activated carbon and solvent regeneration is proposed for investigation. the process offers easier and less costly solvent regneration, reduced adsorber bed-length requirements, reduced concentrations of adsorbed water, and lower process energy… More

Bioengineering processes would benefit significantly from a lower-cost supply of oxygen-enriched air. oxygen is producedon large scale industrially using cryogenic fractionation, but this process is capital intensive and is not economic for smaller scale operations. pressure swing asorption competes… More

Chemical warfare agents pose a threat to our forces which requires a countermeasure which does not restrict the mobility or operating effectiveness of the soldiers and which can be readily deployed. the objectives of the program are the development of specialty formulations which will protect and\… More

Gas separation membranes have recently been commer- cialized and are being used industrially for the recovery of hydrogen, for enriched air production, for enriched nitrogen production, and for acid-gas removal among other applications. membrane processes have the potential for greatly reducing… More

The proposed research is directed at developing a new affinity adsorption and chromatography technique which offers great promise for commercial scale separations of biologically active materials such as interferon and growth hormone. the technique is based on attaching the affinity ligands to a… More

U.s. military forces need protection against chemical warfare agents should these be deployed against them in some future conflict. to this end, an effective gas mask has been developed which provides respiratory protection against all known military toxic chemical agents.the mask uses whetlerite, a… More

There is a requirement for an improved radome material, with a finer grain structure, greater strength at elevated temperatures and greater erosion resistance (particularly to rain) than present materials. this new material must be capable of being fabricated into intricate shapes with accurate… More

Membrane based inert gas generating systems for inerting of fuel tank ullage space to carry a lower aircraft penalty than systems based on molecular sieves and systems based on storage of cryogenic nitrogen. with current technology, approximately 30 lbs of membrane material are necessary per lb/min… More

Future atmospheric entry vehicles will require more durable,lighter, reusable thermal protection to withstand temperature around 1370 k. standard alumina or aluminosilicate refractories have low thermal conductivity and retain structural integrity at this temperature. merix corporation proposes an… More

The objective of this phase i proposal is to discover novel antitumor agents that may offer therapeutic advantages over those currently available. this research program will be based on the chemical synthesis of certain analogs of the antitumor antibiotic fredericamycin a. these analogs may possess… More

In this program, thin sheets of optically clear, ceramic materials will be produced and fabricated into lenses for evaluation as contact lens materials. the materials will permit high oxygen flux to and from the cornea, preventing atoxia and should have high wettability. they will also be strong,… More

Diabetes has a huge medical, social, and economic impact. poor compliance with parenteral insulin administration is a major problem, believed responsible for much of the end-organ damage (eye, brain, and kidney) associated with the disease. oral insulin administration would be a more convenient… More

Colonoscopy is well established as the definitive diagnostic procedure when malignancy of the large intestine is suspected. there is excellent evidence that all or nearly all colonic malignancy begins in previously benign polyps. if these could be removed while still benign, most colon cancer would… More

Diagnosis and treatment of diseases of the small intestine remain difficult and time consuming, with poor patient tolerance and uncertain outcome. currently, 50 to 100 patients with upper gastrointestinal bleeding are admitted to hospitals per 100,000 population per annum. in 5 percentof these… More

Because of new insights into the physical chemistry and pathophysiology of bile acids and other nutrient milieu in the small intestine and new bioengineering approaches to more efficient resins, the development of enormously improved bile acid adsorbents should now be possible. theirdevelopment… More

An improved intracorneal lens, which will avoid both the biocompativility problems of current polysulfone lenses and thickness requirement of current hydrogel lenses, will be developed. the improved lenses will permit a surgically simple, accurate modification of corneal power to correct vision. in… More

Merix proposes a new method to make 3-d multilayer copper on kapton substrates, which can provide a very high density of interconnections between closely packed chips. the new substrate can be used to mount chips in a 2-d array, as in mcm's, or in a 3-d stacked chip array. connections between chips,… More

High power electronics devices such as power switches generate large heat fluxes, which must be removed, or the devices will exceed their upper temperature limits. most cooling methods are incapable of removing such large heat fluxes. merix corporation proposes to develop a high efficiency cooling… More

Diagnosis and treatment of diseases of the small intestine remain difficult and time consuming because of poor patient tolerance and uncertain outcome. Currently 50 to 100 patients with upper gastrointestinal bleeding are admitted to hospitals per 100,000 population per annum. In 5% of these cases,… More

Pressure stabilized arches, consisting of curved fabric tubes with closed ends and a valve for inflation and air retention, show promise as lightweight, quickly-erectable support structures for Army tents. Various methods for producing the pressurized air beams have been explored. The current method… More

Current chemically protective clothing is expensive to produce in part because of the time and labor required to first make sewn seams, and then to hot-air weld adhesive fabric tape over the seams to prevent penetration along the seam thread. Stitchless, ultrasonically-welded fabris seams while as… More

MCM's are common approach to smaller, faster electronics, such as will be required in future space applications. To reduce costs and speed development of MCM-based systems, Cray Research, Inc. has been developing standardized, scalable electronic packaging, suitable for uses ranging from… More