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A NOVEL DIAGNOSTIC TEST FOR IRRITABLE BOWEL SYNDROME

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
60899
Program Year/Program:
2002 / SBIR
Agency Tracking Number:
DK062517
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
METABOLIC SOLUTIONS, INC.
METABOLIC SOLUTIONS, INC. 460 AMHERST ST NASHUA, NH 03063
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2002
Title: A NOVEL DIAGNOSTIC TEST FOR IRRITABLE BOWEL SYNDROME
Agency: HHS
Contract: 1R43DK062517-01
Award Amount: $100,000.00
 

Abstract:

DESCRIPTION (provided by applicant): Irritable Bowel Syndrome (IBS) is a life altering disorder of the intestines that effects approximately 20 percent of the general population. There is no single diagnostic test for positive confirmation of IBS. Physicians arrive at an lBS diagnosis following a protocol that uses standard endoscopic tests to exclude structural or biochemical abnormalities, a physical examination and a symptom questionnaire. This inefficient process leads to an enormous use of healthcare resources estimated at 3.5 million office visits and 2.2 million prescriptions at a direct and indirect cost of $29 billion annually. Our objective is to develop an easy to use, low cost breath test to diagnosis lBS. The test developed by Metabolic Solutions (MSI) is based on the principle that lBS patients malabsorb fructose. In preliminary studies MSI has demonstrated a novel technology using a carbon 13 tracer and unlabeled fructose to identify individuals with lBS by whether or not they can absorb the administered fructose. This is the first test to assay fructose malabsorption directly from the small intestine and correlate it to the diagnosis of LBS. The proposed test will significantly reduce national health care expenditures because proper diagnosis will lead to fewer office visits, more prudent use of drugs and better general health and well-being for a large number of Americans.

Principal Investigator:

David A. Wagner
6035986960
DAVID@METSOL.COM

Business Contact:

Martin Baker
6035986973
MARTINB@METSOL.COM
Small Business Information at Submission:

METABOLIC SOLUTIONS, INC.
METABOLIC SOLUTIONS, INC. 460 AMHERST ST NASHUA, NH 03063

EIN/Tax ID: 043077518
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No