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A Fiber-Optic Evanescent Wave Absorption Organophosphorus Biosensor

Award Information

Agency:
Department of Defense
Branch:
Army
Award ID:
52965
Program Year/Program:
2001 / SBIR
Agency Tracking Number:
A012-0724
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
MetroLaser, Inc.
22941 Mill Creek Drive Laguna Hills, CA -
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2001
Title: A Fiber-Optic Evanescent Wave Absorption Organophosphorus Biosensor
Agency / Branch: DOD / ARMY
Contract: DAAD19-02-C-0033
Award Amount: $69,966.00
 

Abstract:

Organophosphorous compounds (OPC's) have strongly adverse effects on human health and ecosystems, and reliable monitoring of these compounds is of utmost importance. MetroLaser proposes to develop a fiber-optic evanescent wave mid-IR absorption biosensorfor the detection of OPC's with Acetylcholinesterase (AChE) as the sensing material. The proposed sensor is expected to have superior sensitivity, selectivity, and responsivity. To this end, a porous matrix of ordered multi-layers of AChE-coatednano-particles (Quantum Dots, QD's) provide the sensing region. The controlled formation of a thick porous sensing region containing high surface-to-volume ratio QD's ensures minimal sensor-to-sensor variation, maximum responsivity, as well as enhancedmid-IR absorption, and therefore, a substantial increase in sensitivity. It is estimated that the detection limit of the sensor can be made to be in the pM range. Mid-IR

Principal Investigator:

Bauke Heeg
Senior Scientist
9495530688
bheeg@metrolaserinc.com

Business Contact:

Peter DeBarber
Vice President
9495530688
pdebarber@metrolaserinc.com
Small Business Information at Submission:

METROLASER, INC.
18010 Skypark Circle, Suite 100 Irvine, CA 92614

EIN/Tax ID: 330584881
DUNS: N/A
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No