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IDENTIFICATION OF BACTERIA DIRECT FROM BLOOD CULTURE

Award Information

Agency:
Department of Health and Human Services 		Branch:
N/A 		Award ID:
55756 		Program Year/Program:
2001 / SBIR
Agency Tracking Number:
2R44AI046038-02 		Solicitation Year:
N/A 		Solicitation Topic Code:
N/A 		Solicitation Number:
N/A
Small Business Information
MIDI, INC.
MIDI, INC. 125 SANDY DR NEWARK, DE 19713
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2001
Title: IDENTIFICATION OF BACTERIA DIRECT FROM BLOOD CULTURE
Agency: HHS
Contract: N/A
Award Amount: $0.00
 

Abstract:

DESCRIPTION (Verbatim from Applicant's Abstract):Rapid identification of bacteria direct from a blood culture bottle would speed up patient treatment and recovery, thereby also greatly reducing hospital care costs. The current procedure of subculturing typically takes from 24 to 48 hours to obtain bacterial identifications. Gas chromatographic analysis of bacterial fatty acids has promise as a rapid and inexpensive identification technique if the system were more sensitive and if the impact of the blood fatty acids could be minimized. Splitless injection, purification of the air supply, decreased data rate collection and concentration of the sample provide an increase in sensitivity of more than 1,600,000X. Lysis of blood cells by saponin or detergents coupled with filtration greatly reduces contamination of the bacterial fatty acids by blood components. New algorithms show promise for reducing the impact of blood components and for naming the components of polymicrobic cultures. A novel technique for rapid derivatization of fatty acids shows promise of very rapid identification of the pathogens. As patient care costs exceed $1,000 per day, the new technique could produce great health care cost savings. Additionally, by allowing targeted treatment and decreased recovery times, the technique should reduce patient suffering and aid in reducing the number of nosocomial infections. PROPOSED COMMERCIAL APPLICATION: Not Available

Principal Investigator:

Myron Sasser

Business Contact:


3027374297
SASSER@MIDI-INC.COM
Small Business Information at Submission:

MIDI, INC.
125 SANDY DR NEWARK, DE 19713

EIN/Tax ID: 510339655
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No