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SBIR Phase I: Feasibility assesment for Stachybotrys chartarum and Aspergillus…

Award Information

Agency:
National Science Foundation
Branch:
N/A
Award ID:
58260
Program Year/Program:
2002 / SBIR
Agency Tracking Number:
0215114
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
MICROBIAL INSIGHTS INC
2340 STOCK CREEK BLVD ROCKFORD, TN 37853-3304
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2002
Title: SBIR Phase I: Feasibility assesment for Stachybotrys chartarum and Aspergillus fumigatus ELISA kits
Agency: NSF
Contract: N/A
Award Amount: $52,565.00
 

Abstract:

This Small Business Innovation Research (SBIR)Phase I project will investigate a biotechnological approach to rapidly detect two notorious toxin-producing fungi. Indoor fungal growth related to water leaks and floods can induce a variety of disease symptoms. The presence of some fungi, like Stachybotrys chartarum , can cause severe morbidity. Unfortunately, the detection of harmful fungi, like Stachybotrys, has been hampered by inadequate methods. The proposed research will determine the feasibility of developing a rapid detection method for toxigenic fungi that could be used at any test site. The primary objective of this research is to isolate a diffusible spore molecule from S. chartarum spores and one from A. fumigatus spores for the development of an antibody-based detection kit. The molecules will be extracted in saline solution to mimic diffusion into lung linings and used for polyclonal antibody development. If successful, the antigens will be used for monoclonal antibody development in a Phase II project. This will allow for the development of a rapid, on-site testing kit to detect potentially dangerous fungal organisms quickly and inexpensively. The commercial application of this project will be in the area of diagnostics linked to human health and animal health.

Principal Investigator:

Yvette M. Piceno
8655738188
yvette.piceno@microbe.com

Business Contact:

Small Business Information at Submission:

Microbial Insights Inc
2340 Stock Creek Blvd. Rockford, TN 37853

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No