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COMPUTER MICROSCOPY AND NEUROINFORMATICS SYSTEM

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
54601
Program Year/Program:
2001 / SBIR
Agency Tracking Number:
1R43MH062840-01
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
MICROBRIGHTFIELD, INC.
185 ALLEN BROOK LN, STE 201 WILLISTON, VT -
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2001
Title: COMPUTER MICROSCOPY AND NEUROINFORMATICS SYSTEM
Agency: HHS
Contract: N/A
Award Amount: $100,000.00
 

Abstract:

DESCRIPTION: We will develop a neuroinformatics system that will allow neuroscientists to collect extremely large images of microscopic specimens at the highest magnification of a light microscope, to store them in a web-enabled database, and to share them with colleagues and students over the Internet and intranets. Once collected, these extremely large images will be in effect, "virtual slides." The virtual slides, composed of thousands of fields of view, will enable researchers to view complete tissue specimens at any level of magnification. Important information about the brain often requires examination of a specimen at several different magnifications. For instance, low magnification is required to identify large anatomical regions while higher magnification is required to identify finer structure, such as individual cells, dendrites, spines, etc. Our innovative system will provide new opportunities for the neuroscience community to share research over the Internet. In Phase II we expect to expand the system: to use illumination techniques other than brightfield (e.g. fluorescence); to merge virtual slides obtained from multi-illumination techniques into a multi-layer virtual slide; and to combine graphic overlays with virtual slides to create high-resolution atlases. PROPOSED COMMERCIAL APPLICATION: Internet system for archiving and comparing images for clinical pathology; commercial web sites for education and research within an beyond the neuroscience area; a service to create and maintain the virtual slides and database for a customer's web site; and creation of large-scale images for text books and stereotaxic atlases.

Principal Investigator:

Jacob R. Glaser

Business Contact:


8026559360
JGLASER@MICROBRIGHTFIELD.COM
Small Business Information at Submission:

MICROBRIGHTFIELD, INC.
74 HEGEMAN AVE COLCHESTER, VT 05446

EIN/Tax ID: 521609586
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No