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Ink-Jet Printed Nerve Conduits

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
66663
Program Year/Program:
2003 / SBIR
Agency Tracking Number:
NS040625
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
MicroFab Technologies Inc
1104 Summit Avenue Suite 110 Plano, TX -
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2003
Title: Ink-Jet Printed Nerve Conduits
Agency: HHS
Contract: 2R44NS040625-02
Award Amount: $0.00
 

Abstract:

DESCRIPTION (provided by applicant): Paralysis and loss of nerve function through trauma highlight the need for implantable device capable of restoring nerve function, without increasing tissue damage by requiring autologous nerve grafts. This study focuses on enhancing nerve regeneration in two ways First, fabrication precision and control for nerve guidance conduits will be increased This will result in nerve conduits that bioabsorb in eight weeks, resist in vivo compression through printed external support structures, and have uniform porosity Second, an NGF gradient within the conduit will be created by using high-precision ink jets NGF-enriched polymer will be deposited into a digitally controlled pattern. Achievement of the aims of this project will result in fabrication of nerve guidance conduits with the above-mentioned features and verification of nerve regeneration in animal models. The research plan will be carried out at three institutions MicroFab, University of Texas, Austin, and University of California, Irvine. Nerve conduits will be modeled, designed, fabricated and tested at MicroFab, they will be further characterized and in vitro studies will be carried out at University of Texas, and in vivo experiments, Walking-Track analysis, and electrophysiological studies will be carried out at University of California, Irvine. Proven cooperation among these three groups will insure project success.

Principal Investigator:

Donald J. Hayes
9725788076
DHAYES@MICROFAB.COM

Business Contact:

David Wallace
9725788076
DWALLACE@MICROFAB.COM
Small Business Information at Submission:

MICROFAB TECHNOLOGIES, INC.
MICROFAB TECHNOLOGIES, INC. 1104 SUMMIT AVE, STE 110 PLANO, TX 75074

EIN/Tax ID: 751968264
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No