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EXPRESSION OF FOREIGN GENES IN WHOLE INSECTS USING RECOMBINANT BACULOVIRUS

Award Information

Agency:
Department of Agriculture
Branch:
N/A
Award ID:
4647
Program Year/Program:
1987 / SBIR
Agency Tracking Number:
4647
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Microgenesys Inc.
400 Frontage Rd W Haven, CT 06516
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 2
Fiscal Year: 1987
Title: EXPRESSION OF FOREIGN GENES IN WHOLE INSECTS USING RECOMBINANT BACULOVIRUS
Agency: USDA
Contract: N/A
Award Amount: $210,000.00
 

Abstract:

BACULOVIRUSES HAVE GREAT POTENTIAL AS INSECT CONTROL AGENTS BY THEIR INHERENT SELECTIVITY AND SAFETY. RECOMBINANT BACUL OVIRUSES EXPRESSING FOREIGN GENES ENCODING FOR INSECTICIDAL PROTEINS SHOULD BE CONSIDERABLY MORE EFFECTIVE BIOLOGICAL CONTROL AGENTS THAN WILD-TYPE VIRUSES IN BOTH FIELD EFFICACYAND HOST RANGE. THE AIM OF THE PROPOSED RESEARCHIS TO INVESTINGATE THE BIOLOGY AND EFFECTS OR RECOMBINANT VIRUSES IN WHOLE INSECTS. AN EASILY ASSAYABLE GENE (B-GALACTOSIDASE), SEVERAL ACMNPV RECOMBINANTS, AND SUBCEPTIBLE LEPIDOPTERAN LARVAE WILL BE USED A MODEL MATERIALS. SUCH QUESTIONS AS THE TIME COURSE, SITE AND QUANTITY OF GENE EXPRESSION AND THE STABILITY OF VIRUS RECOMBINANTS FOLLOWING REPEATED PASSAGES, WILL BE ANSWERED.

Principal Investigator:


0

Business Contact:

Dr. mark a. cochran
Small Business Information at Submission:

Microgenesys, Inc.
400 Frontage Rd West Haven, CT 06516

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No