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CHEMOTHERAPY OF LEISHMANIA WITH OLIQODEOXYNUCLEOTIDE PROBES

Award Information

Agency:
Department of Defense
Branch:
Army
Award ID:
8864
Program Year/Program:
1990 / SBIR
Agency Tracking Number:
8864
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Epoch Pharmaceuticals, Inc.
1725 220TH ST SE, 104 Bothell, WA 98052
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 2
Fiscal Year: 1990
Title: CHEMOTHERAPY OF LEISHMANIA WITH OLIQODEOXYNUCLEOTIDE PROBES
Agency / Branch: DOD / ARMY
Contract: N/A
Award Amount: $563,537.00
 

Abstract:

WE WILL INVESTIGATE THE ABILITY OF OLIGODEOXYNUCLEOTIDES COMPLEMENTARY TO THE SPLICED LEADER SEQUENCE OF LEISHMANIA ENRIETTII TUBULIN MRNA'S TO INHIT TRANSLATION AND TO KILL THE CELLS IN CULTURE. VARIOUS CHEMICAL MODIFICATIONS WILL BE MADE TO ENHANCE THE EFFECT OF THE OLIGOS. SUCCESSFUL AGENTS MAY BE VALUABLE, SELECTIVE CHEMOTHERAPEUTIC AGENTS AGAINST OTHER LEISHMANIA SPECIES IF MAD COMPLEMENTARY TO MRNA LEADERS FROM THOSE SPECIES.

Principal Investigator:

Dr Rich B Meyer Jr
2064858566

Business Contact:

Small Business Information at Submission:

Micro-probe Corp.
1725 - 220th St Se/#104 Bothell, WA 98021

EIN/Tax ID:
DUNS: N/A
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No