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SBIR Phase II: Membrane Protein Microarrays

Award Information

Agency:
National Science Foundation
Branch:
N/A
Award ID:
63408
Program Year/Program:
2005 / SBIR
Agency Tracking Number:
0318938
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
MICROSURFACES INC
3913 Todd Lane SUITE 102 Austin, TX 78744-
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Woman-Owned: Yes
Minority-Owned: Yes
HUBZone-Owned: No
 
Phase 2
Fiscal Year: 2005
Title: SBIR Phase II: Membrane Protein Microarrays
Agency: NSF
Contract: 0450262
Award Amount: $500,000.00
 

Abstract:

This Small Business Innovation Research (SBIR) Phase II project proposes to develop a product platform based on polymer cushion coated glass slides with controlled surface charge density for membrane protein microarray fabrication. The key technical objectives for Phase II research are : (a) to complete quantitative studies on surface charge density in the formation of supported phospholipid bilayer (SPB) from charged lipids , (b) to develop the chemistry for the grafting / adsorption of polymer cushions, (c) to measure the activities of membrane proteins in SPBs, and (d) to fabricate membrane protein microarrays based on surface pre-patterning using soft lithography techniques. The commercial application of this project will be in the area of protein microarrays for use in disease diagnostics and for drug discovery research. The proposed technology will enable development of therapeutics aimed at membrane protein targets.

Principal Investigator:

Athena Guo
Dr
6127890104
athena@memsurface.com

Business Contact:

Athena Guo
Dr
6127890104
athena@memsurface.com
Small Business Information at Submission:

MSI (Microsurfaces Inc)
4001 Stinson Blvd. Minneapolis, MN 55421

EIN/Tax ID:
DUNS: N/A
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No