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SYNTHESIS AND BIOMEDICAL APPLICATIONS OF FLUORESCENT PROBES

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
4942
Program Year/Program:
1989 / SBIR
Agency Tracking Number:
4942
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
MOLECULAR PROBES, INC.
MOLECULAR PROBES, INC. 4849 PITCHFORD AVE EUGENE, OR 97402
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 2
Fiscal Year: 1989
Title: SYNTHESIS AND BIOMEDICAL APPLICATIONS OF FLUORESCENT PROBES
Agency: HHS
Contract: N/A
Award Amount: $500,000.00
 

Abstract:

MOLECULAR PROBES AIMS TO DEVELOP SEVERAL NEW FLUORESCENT PROBES OF UTILITY IN MANY AREAS. FLUORESCENT DYES HAVE EXTENSIVE APPLICATIONS FOR DETERMINATION OF BIOMOLECULAR STRUCTURES AND MECHANISMS, CELL PROPERTIES AND INTERACTIONS,NORMAL AND DISEASE STATES, AND AS ULTRASENSITIVE VISIBLE TRACERS. NEW DYES ARE REQUIRED FOR GREATER SENSITIVITY AND SPECIFICITY OF DETECTION, IMPROVED SPECTRAL PROPERTIES, AND TO FACILITATE APPLICATIONS OF RECENT DEVELOPMENTS IN LOW- COST EXCITATION SOURCES. OTHER DYES ARE DESIGNED FOR LABELING SINGLE CELLS, CONTROLLED RELEASE OF DYES AND DRUGS INSIDE CELLS, AND SPECIFIC INVESTIGATIONS OF TUBULIN, ADRENERGIC RECEPTORS, AND AN ENZYME. THE NEW PROBES WILL BESYNTHESIZED AND CHARACTERIZED BY MOLECULAR PROBES, THEN EVALUATED FOR THEIR BIOCHEMICAL EFFECTIVENESS IN COLLABORA- TION WITH SEVERAL OUTSIDE RESEARCH GROUPS. AN ADVISORY COMMITTEE WILL BE FORMED TO SEEK FURTHER COLLABORATIONS ON DEVELOPMENT OF FLUORESCENCE APPLICATIONS AND TO GUIDE FUTURERESEARCH EFFORTS OF THE COMPANY.

Principal Investigator:

Dr Richard P Haugland
Principal Investigator
5039986254

Business Contact:

Small Business Information at Submission:

Molecular Probes Inc.
4849 Pitchford Ave Eugene, OR 97402

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No