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Company Information:

Company Name: MycoTox, Inc.
City: Denver
State: CO
Zip+4: 00000 0802
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Website URL: N/A
Phone: N/A

Award Totals:

Program/Phase Award Amount ($) Number of Awards
SBIR Phase I $945,680.00 12
SBIR Phase II $671,260.00 1
STTR Phase I $82,912.00 1

Award List:

ZEAMATIN: A POSSIBLE HUMAN THERAPEUTIC ANTIFUNGAL AGENT

Award Year / Program / Phase: 1990 / SBIR / Phase I
Agency: HHS
Principal Investigator: Claude P Selitrennikoff
Award Amount: $50,000.00
Abstract:
A 22-kda protein that has potent activity against a number of clinically important human pathogens has been isolated from maize seeds. in addition, this protein, named zeamatin, has the unique ability to synergize with known antifungal drugs, decreasing the dose required for fungal cell killing… More

Antisense Inhibition Of Fungal Growth

Award Year / Program / Phase: 1993 / SBIR / Phase I
Agency: HHS
Principal Investigator: Carol S. Enderlin
Award Amount: $50,000.00
Abstract:
Immunocompromised patients provide perhaps the greatest challenge to modern health care; these patients are susceptible to infections by organisms that are normally harmless commensals. Treatment of fungal infections is difficult due to a lack of effective antifungal antibiotics. Even after 29 years… More

In Vitro Screen for Fungal Glucan Synthase Inhibitors

Award Year / Program / Phase: 1993 / SBIR / Phase I
Agency: HHS
Principal Investigator: Claude P. Selitrennikoff
Award Amount: $32,750.00

In Vitro Screen for Fungal Glucan Synthase Inhibitors

Award Year / Program / Phase: 1995 / SBIR / Phase II
Agency: HHS
Principal Investigator: Claude P. Selitrennikoff
Award Amount: $671,260.00
Abstract:
Fungi are medically and economically very important, contributing to waste, spoilage and disease. Treatment of human fungal disease, especially in immunodeficient patients suffering from Acquired Immunodeficien- cy Syndrome, is hampered by the virtual lack of clinically useful drugs. Filamentous… More

Rapid Simple Fungal Diagnostic

Award Year / Program / Phase: 1995 / SBIR / Phase I
Agency: HHS
Principal Investigator: Claude Selitrennikoff
Award Amount: $100,000.00
Abstract:
We will develop a simple, rapid quantitative test for the presence of a water-soluble fungal-specifdiagnostic that will be useful for detecting both acute, life-threatening infections as well as subaThis test exploits the observation that when Candida albicans yeast cells divide, soluble… More

Expression of Plant Genes in Neurospora crassa

Award Year / Program / Phase: 1995 / SBIR / Phase I
Agency: USDA
Principal Investigator:
Award Amount: $55,000.00
Abstract:
Plants represent a largely untapped reservoir of therapeutic and other agents. Of the 250,000 to 300,000 plant species, only 5000 have been examined for medically useful compounds. Agents discovered include cardioactive steroids, vasoactive compounds, antineoplastic agents, e.g., taxol,… More

SCREEN FOR FUNGAL KETOL/ISOMERASE INHIBITORS

Award Year / Program / Phase: 1996 / SBIR / Phase I
Agency: HHS
Principal Investigator:
Award Amount: $96,390.00

NOVEL ANTIFUNGAL SCREENS--EXPRESSION INHIBITORS

Award Year / Program / Phase: 1997 / SBIR / Phase I
Agency: HHS
Principal Investigator: Agnan, jacqueline
Award Amount: $97,214.00

NOVEL ANTIFUNGAL SCREEN--CELL WALL REGULATION INHIBITORS

Award Year / Program / Phase: 1997 / SBIR / Phase I
Agency: HHS
Principal Investigator: Selitrennikoff, claude p
Award Amount: $99,420.00

ZEAMATIN, AN ANTIFUNGAL THERAPEUTIC

Award Year / Program / Phase: 1997 / SBIR / Phase I
Agency: HHS
Principal Investigator: Selitrennikoff, claude p
Award Amount: $99,980.00

IN VITRO ASSAYS FOR FUNGAL TRANSDUCTION KINASES

Award Year / Program / Phase: 1997 / SBIR / Phase I
Agency: HHS
Principal Investigator: Tentler, john j
Award Amount: $99,926.00

SCREENING OF THERMOPHILES FOR ANTIFUNGAL ACTIVITY

Award Year / Program / Phase: 1997 / SBIR / Phase I
Agency: HHS
Principal Investigator: Selitrennikoff, claude p
Award Amount: $100,000.00

EVALUATION OF ZEAMATIN AS AN ANTIFUNGAL THERAPEUTIC

Award Year / Program / Phase: 1998 / STTR / Phase I
Agency: HHS
Research Institution: CA Institute For Medical Research
Principal Investigator: Selitrennikoff
Award Amount: $82,912.00
RI Contact: N/A

Development of a Corn Protein, Zeamatin, as a Novel Antifungal Pharmaceutical

Award Year / Program / Phase: 1998 / SBIR / Phase I
Agency: USDA
Principal Investigator: Selitrennikoff , Principal Investigator
Award Amount: $65,000.00