Fiscal Year:
2002
Title:
IMPROVED MRI CONTRAST AGENTS
Agency:
HHS
Contract:
1R43CA094495-01
Award Amount:
$185,313.00
Abstract:
A new class of MRI contrast agents has been discovered and synthesized by Nanoprobes. Initial MRI animal studies showed excellent definition of some types of brain tumors, which were
undetectable with the commonly used agent, gadodiamide. Furthermore, initial
toxicity studies showed the agents to be non-toxic. One new agent was coupled
to antibodies and showed high delivery to antigen on bench tests, indicating
hope for development of targeted contrast agents for functional MRI. This
project will focus on continued development including chemical synthesis,
purification, chemical and magnetic characterization, in vivo animal studies,
and antibody targeting of the agents in vivo.
Small Business Information at Submission:
NANOPROBES, INC.
NANOPROBES, INC. 95 HORSEBLOCK RD YAPHANK, NY 11980
EIN/Tax ID:
113038451
DUNS:
N/A
Number of Employees:
N/A
Woman-Owned:
No
Minority-Owned:
No
HUBZone-Owned:
No