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IMPROVED MRI CONTRAST AGENTS

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
59895
Program Year/Program:
2002 / SBIR
Agency Tracking Number:
CA094495
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
NANOPROBES, INC.
95 HORSEBLOCK RD YAPHANK, NY 11980-
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2002
Title: IMPROVED MRI CONTRAST AGENTS
Agency: HHS
Contract: 1R43CA094495-01
Award Amount: $185,313.00
 

Abstract:

A new class of MRI contrast agents has been discovered and synthesized by Nanoprobes. Initial MRI animal studies showed excellent definition of some types of brain tumors, which were undetectable with the commonly used agent, gadodiamide. Furthermore, initial toxicity studies showed the agents to be non-toxic. One new agent was coupled to antibodies and showed high delivery to antigen on bench tests, indicating hope for development of targeted contrast agents for functional MRI. This project will focus on continued development including chemical synthesis, purification, chemical and magnetic characterization, in vivo animal studies, and antibody targeting of the agents in vivo.

Principal Investigator:

James F. Hainfeld
6312059490
HAINFELD@NANOPROBES.COM

Business Contact:

James Hainfeld
6312059490
HAINFELD@NANOPROBES.COM
Small Business Information at Submission:

NANOPROBES, INC.
NANOPROBES, INC. 95 HORSEBLOCK RD YAPHANK, NY 11980

EIN/Tax ID: 113038451
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No