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Three energy sources that will work in a cold, dark, static environment

Award Information

Agency:
Department of Defense
Branch:
Office of the Secretary of Defense
Award ID:
54725
Program Year/Program:
2001 / SBIR
Agency Tracking Number:
O012-0187
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
NanoSonic, Inc.
158 Wheatland Drive Pembroke, VA 24136-
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2001
Title: Three energy sources that will work in a cold, dark, static environment
Agency / Branch: DOD / OSD
Contract: DAMD17-02-C-0007
Award Amount: $99,999.00
 

Abstract:

The purpose of the proposed OSD Phase I program is to develop and commercialize novel tissue solders based on a biodegradable copolymer system that contains a controlled degree of acrylate-terminated photoactive branch sites. This will result in a processthat, with the addition of a biocompatible and non-toxic photosensitizer/electron donor initiating system, will rapidly cure from a viscous liquid to a tough ductile polymer in a matter of milliseconds. This reaction occurs with a minimal heat ofpolymerization in an oxygen-containing aqueous environment at physiological pH. The free-radical cure reaction is easily triggered by applying a filtered and focused light beam via optical fiber from a source with a broad wavelength range to the syntheticsolder (polymer/initiator) formulation. Utilization of a specified fiber type allows control of this range such that the surrounding tissue is not subjected to potentially damaging wavelengths that are frequently a problem associated with laser systems.Addition of a light sensitive dye to the formulation serves as a visual cue to the surgeon as an indicator of cure conversion. As the dye changes color, visual feedback is provided to the surgeon indicating the completion of the procedure. The purpose ofthe proposed OSD Phase I program is to develop and commercialize novel tissue solders based on a biodegradable copolymer system that contains a controlled degree of acrylate-terminated photoactive branch sites. This will result in a process that, with theaddition of a biocompatible and non-toxic photosensitizer/electron donor initiating system, will rapidly cure from a viscous liquid to a tough ductile polymer in a matter of milliseconds. This reaction occurs with a minimal heat of polymerization in anoxygen-containing aqueous environment at physiological pH. The free-radical cure reaction is easily triggered by applying a filtered and focused light beam via optical fiber from a source with a broad wavelength range to the synthetic solder(polymer/initiator) formulation. Utilization of a specified fiber type allows control of this range such that the surrounding tissue is not subjected to potentially damaging wavelengths that are frequently a problem associated with laser systems. Additionof a light sensitive dye to the formulation serves as a visual cue to the surgeon as an indicator of cure conversion. As the dye changes color, visual feedback is provided to the surgeon indicating the completion of the procedure.

Principal Investigator:

Jeffrey Mecham
Research Scientist
5409531785
jbmecham@nanosonic.com

Business Contact:

Richard Claus
President
5409531785
roclaus@nanosonic.com
Small Business Information at Submission:

NANOSONIC, INC.
P.O. Box 618 Christiansburg, VA 24068

EIN/Tax ID: 541877635
DUNS: N/A
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No