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Photo-curable Biodegradable-based Tissue Solders containing a Photochromic…

Award Information

Department of Defense
Office of the Secretary of Defense
Award ID:
Program Year/Program:
2002 / SBIR
Agency Tracking Number:
Solicitation Year:
Solicitation Topic Code:
Solicitation Number:
Small Business Information
Nanosonic, Inc.
VA Pembroke, VA 24136-3645
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: Yes
Phase 2
Fiscal Year: 2002
Title: Photo-curable Biodegradable-based Tissue Solders containing a Photochromic Endpoint Indicator
Agency / Branch: DOD / OSD
Contract: DAMD17-02-C-0007
Award Amount: $750,000.00


"The purpose of the proposed Army Phase II program is to develop and commercialize novel tissue solders based on a biodegradable copolymer system that contains a controlled degree of acrylate-terminated photoactive branch sites. This will result in aprocess that, with the addition of a biocompatible and non-toxic photosensitizer /electron donor initiating system, will rapidly cure from a viscous liquid to a tough ductile polymer in a matter of milliseconds. This reaction occurs with a minimal heat ofpolymerization in an oxygen-containing aqueous environment at physiological pH. The free-radical cure reaction is easily triggered by applying a filtered and focused light beam of known power via optical fiber from a source with a broad wavelength range tothe synthetic solder (polymer/initiator) formulation. During Phase II, we would work with a biomedical institute partner and investor to further develop the tissue solder system by maximizing adhesion, minimizing cure/illumination time, and maximize watertransfer in the resulting system. Additionally, we plan to investigate an alternative biocompatible photosensitive endpoint indicator that responds (via cure) to visible wavelength stimulation and continue development of a compact light emittingdiode-based photon delivery system that can be easily integrated into existing soldier-based light sources."

Principal Investigator:

Jeffrey Mecham
Research Scientist

Business Contact:

Richard Claus
Small Business Information at Submission:

Nanosonic, Inc.
P.O. Box 618 Christiansburg, VA 24068

EIN/Tax ID: 541877635
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No