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THE PURPOSE OF THIS PROJECT IS TO LABEL MONOCLONAL ANTIBODIES WITH ASTATINE-211…

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
4812
Program Year/Program:
1986 / SBIR
Agency Tracking Number:
4812
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
NEORX CORPORATION
410 W HARRISON ST SEATTLE, WA 98119
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1986
Title: THE PURPOSE OF THIS PROJECT IS TO LABEL MONOCLONAL ANTIBODIES WITH ASTATINE-211 FOR USE IN RADIO-IMMUNOTHERAPY.
Agency: HHS
Contract: N/A
Award Amount: $50,000.00
 

Abstract:

THE PURPOSE OF THIS PROJECT IS TO LABEL MONOCLONAL ANTIBODIES WITH ASTATINE-211 FOR USE IN RADIO-IMMUNOTHERAPY.THE GOAL OF THE PROPOSED RESEARCH IS TO DEVELOP A METHOD TO INCORPORATE ASTATINE INTO ANTIBODIES SUCH THAT THE ASTATINE LABILE IN VITRO OR IN VIVO. IN THE INVESTIGATION, TWO DIFFERENT APPROACHES TO LABELING WILL BE COMPARED. ONE APPROACH WILL BE DIRECT LABELING WITH ASTATINE; THE OTHER APPROACH WILL INVOLVE THE USE OF ASTATINATED SMALL MOLECULES. THE LATTER APPROACH WILL INCLUDE DEVELOPMENT OF METHODS TO FIRMLY ATTACH THE ASTATINE TO THE SMALL MOLECULES.

Principal Investigator:

D scott wilbur
PRINCIPAL INVESTIGATOR
2062817001

Business Contact:

Small Business Information at Submission:

Neorx Corp
410 West Harrison Street Seattle, WA 98119

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No