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DEVELOPMENT OF A NEW CORNEAL AESTHESIOMETER AND NORMS

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
7259
Program Year/Program:
1987 / SBIR
Agency Tracking Number:
7259
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Neurocommunication Research
36 Mill Plain Road Danbury, CT 06811
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1987
Title: DEVELOPMENT OF A NEW CORNEAL AESTHESIOMETER AND NORMS
Agency: HHS
Contract: N/A
Award Amount: $50,000.00
 

Abstract:

DURING PHASE I, THE CREATION OF A SAFE, VALID, PRECISE, RELIABLE, RESEARCH PROTOTYPE INSTRUMENT FOR TESTING THE SOMATOSENSATION OF CORNEA, SCLERA, CONJUNCTIVA, AND EYELID IS EXPECTED. THE SPECIFIC AIMS OF PHASE I ARE TO: (1) MODIFY THE EXISTING WEINSTEIN ORAL MICROAESTHESIOMETER TO CREATE A NEW INSTRUMENT, A CORNEAL MICROAESTHESIOMETER, FOR TESTING CORNEAL SOMATOSENSATION; (2) DEMONSTRATE VALIDITY AND TEST-RETEST RELIABILITY; (3) DEVELOP NORMS ON ASMALL GROUP OF SUBJECTS; (4) EXPLORE THE FEASIBILITY OF OBTAINING CORTICAL EVOKED POTENTIALS; AND (5) EXPLORE, AS AVAILABLE IN THE SAMPLE, THE EFFECTS OF AGE, SEX, CONTACT LENSES, USE OF TOBACCO, AND USE OF ALCOHOL UPON CORNEAL THRESHOLDS. THE LONG-TERM OBJECTIVE IS TO ESTABLISH THE CORNEAL MICROAESTHESIOMETER TEST AS AN OFFICE PROCEDURE FOR SCREENING PATIENTS FOR: (1) SYSTEMIC, OCULAR, OR CORNEAL PROBLEMS; (2) FOR PREDICTING RECOVERY FROM SURGERY; AND (3) FOR EVALUATING IDEAL OPHTHALMIC DOSING ON AN INDIVIDUAL PATIENT BASIS. THE POTENTIAL EXISTS FOR THE DEVELOPMENT OF A CORNEAL AESTHESIOMETER THAT WILL NOT INJURE NEWLY TRANSPLANTED CORNEAS, THAT WILL NOT ELICIT APPREHENSION IN PATIENTS, AND THAT WILL GIVE VALID, PRECISE, AND RELIABLE TESTS. FURTHER, THE NEW CORNEAL AESTHESIOMETER COULD BE USED TO ELICIT CORTICAL EVOKED POTENTIALS FOR THE EVALUATION OF INFANTS OR OF MENTALLY IMPAIRED PATIENTS. IN ADDITION, THE FOLLOWING DISADVANTAGES OF CURRENT CORNEAL AESTHESIOMETERS WILL BE AVOIDED WITH THIS INSTRUMENT: (1) RISK OF TRANSMISSION OF INFECTION; (2) INABILITY TO DELIVER SUBTHRESHOLD STIMULATION; AND (3) INDUCING APPREHENSION IN THE PATIENT FROM A VISUALLY APPROACHING STIMULUS.

Principal Investigator:

Sidney weinstein phd
2037447474

Business Contact:

Small Business Information at Submission:

Neurocommunication Res Lab Inc
West Kenosia Avenue Danbury, CT 06810

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No