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Company Information:
Name:
NEUROP, INC.
Address:
58 Edgewood Road
ATLANTA, GA 30303-
ATLANTA, GA 30303-
Located in HUBZone:
No
Woman-Owned:
No
Minority-Owned:
No
URL:
N/A
Phone:
N/A
Award Totals:
Award List:
In vivo proof of concept:pH-dependent neuroprotection
Award Year / Program / Phase:
2004 / SBIR / Phase I
Agency:
HHS
Principal Investigator:
Mark S. Washburn
Award Amount:
$100,000.00
Abstract:
DESCRIPTION (provided by applicant): Neurodegeneration accompanying stroke and certain types of seizure is a significant problem that has been refractory to treatment despite intensive investigation in both the public and private sector. Neuronal degeneration in animal models can be substantially… More
pH-Sensitive Glutamate Receptor Inhibitors: Clinical Candidate Selection
Award Year / Program / Phase:
2006 / SBIR / Phase II
Agency:
HHS
Principal Investigator:
Scott Myers
Award Amount:
$1,403,583.00
Abstract:
DESCRIPTION (provided by applicant): Ischemic injury of the brain is a major cause of death and morbidity, and often causes long term disability. NMDA receptor (NMDAR) blockers, particularly targeting the NR2B-subunit are neuroprotective in ischemic disease animal models. Unfortunately, most NMDAR… More
Neuroprotection of pH Sensitive NMDAR Antagonists in Cardiopulmonary Bypass Surge
Award Year / Program / Phase:
2007 / SBIR / Phase I
Agency:
HHS
Principal Investigator:
Scott Myers
Award Amount:
$125,788.00
Abstract:
DESCRIPTION (provided by applicant): Heart operations involving the use of cardiopulmonary bypass (CPB) are among the most common surgical procedures in the world, with over 500,000 performed in the U.S. alone in 2000. Such procedures carry a significant r
isk of cerebral injury including death,… More
Evaluation of pH Dependent Neuroprotectants in SAH Model
Award Year / Program / Phase:
2008 / STTR / Phase I
Agency:
HHS
Research Institution:
N/A
Principal Investigator:
Award Amount:
$144,137.00
RI Contact:
N/A
Abstract:
DESCRIPTION (provided by applicant): The goal of this STTR project is to determine if NeurOp's pH-sensitive NMDAR antagonists improve functional recovery and reduce neuronal injury in a validated murine model of vasospasm following subarachnoid hemorrhage
(SAH). Subarachnoid hemorrhage (SAH)… More
Pre-clinical Development of a Context-Dependent NMADR Neuroprotectant for Treatme
Award Year / Program / Phase:
2011 / SBIR / Phase I
Agency:
HHS
Principal Investigator:
George W. Koszalka – 404-941-2360
Award Amount:
$299,541.00
Abstract:
DESCRIPTION (provided by applicant): Cerebral ischemia is a major cause of death and long-term disability, with high accompanying social and medical costs. Approximately 795,000 Americans suffer a stroke each year at an estimated annual cost of 73.7B (American Heart Association. Heart Disease and… More
Pre-clinical Development of a Context-Dependent NMADR Neuroprotectant for Treatme
Award Year / Program / Phase:
2012 / SBIR / Phase II
Agency:
HHS
Principal Investigator:
George W. Koszalka – 404-941-2360
Award Amount:
$2,675,001.00
Abstract:
DESCRIPTION (provided by applicant): Cerebral ischemia is a major cause of death and long-term disability, with high accompanying social and medical costs. Approximately 795,000 Americans suffer a stroke each year at an estimated annual cost of 73.7B (American Heart Association. Heart Disease and… More
Optimization of Novel NR2C and NR2D subunit-selective NMDA receptor potentiators
Award Year / Program / Phase:
2012 / SBIR / Phase I
Agency:
HHS
Principal Investigator:
Scott J. Myers – 404-941-2350
Award Amount:
$691,992.00
Abstract:
DESCRIPTION (provided by applicant): Schizophrenia is a chronic neurological disorder that affects approximately 1% of the world population and causes gt 60 billion dollars of direct and indirect societal costs in the US alone (Wu et al., 2005). Current therapies to treat this disorder have been… More