NON-INVASIVE BORON IMAGING IN HUMAN BRAIN WITH MRI

Award Information

Agency: Department of Health and Human Services	Branch: N/A	Award ID: 19374	Program Year/Program: 1993 / SBIR
Agency Tracking Number: 19374	Solicitation Year: N/A	Solicitation Topic Code: N/A	Solicitation Number: N/A

Small Business Information: Neutron Technology
877 Main Street, #303 Boise, ID 83702
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Woman-Owned: No

Minority-Owned: No

HUBZone-Owned: No

Phase 2: Fiscal Year: 1993

Title: NON-INVASIVE BORON IMAGING IN HUMAN BRAIN WITH MRI

Agency: HHS

Contract: N/A

Award Amount: $500,000.00

Abstract:
BORON NEUTRON CAPTURE THERAPY (BNCT) OPTIMIZATION REQUIRES KNOWLEDGE OF TUMOR-BORON UPTAKE AND ELIMINATION KINETICS AND CONCENTRATIONS. AT PRESENT, THIS KNOWLEDGE IS OBTAINED THROUGH INVASIVE METHODS. THROUGH A NONINVASIVE METHOD, MULTIPLE DATA POINTS CAN BE OBTAINED OVER TIME WITHOUT DISTURBING THE BIOLOGICAL ENVIRONMENT. INITIAL STUDIES HAVE SHOWN THAT MAGNETIC RESONANCE IMAGING (MRI) CAN BE USED AS A NONINVASIVE TOOL TO DETERMINE BORON CONCENTRATION AS A FUNCTION OF TIME AND LOCATION. WE WILL DEVELOP A NEW NONINVASIVE TECHNIQUE USING BORON MRI FOR THE PURPOSE OF IMPROVING THE RESEARCHER'S ABILITY TO CONDUCT BORON PHARMACOKINETIC STUDIES.

Principal Investigator:
Kenneth M Bradshaw
8015817027

Business Contact:

Small Business Information at Submission:

Neutron Technology
50 North Medical Drive Ac-213 Salt Lake City, UT 84132

EIN/Tax ID:

DUNS: N/A

Number of Employees: N/A

Woman-Owned: No

Minority-Owned: No

HUBZone-Owned: No