DESCRIPTION (provided by applicant): The availability of a reference human genome sequence provides the foundation for studying the genetic and molecular basis of human health and disease. Using a variety of modern technologies to study differential gene expression, large numbers of researchers in… More
DESCRIPTION (provided by applicant): The Human Genome Project has brought the field of functional genomics to the forefront of biological and pharmaceutical research. However, deciphering the function(s) of each gene in a high throughput format is complicated by alternative splicing and post-… More
Award Year / Program / Phase:2008 / SBIR / Phase I
Agency:HHS
Principal Investigator:
Award Amount:$578,784.00
Abstract:
DESCRIPTION (provided by applicant): Humans develop natural antibodies against a sugar molecule called Gal, which is present on proteins and lipids in most other species. These antibodies represent one of the strongest natural barriers to infection with ba
cteria, parasites and viruses. NewLink… More
DESCRIPTION (provided by applicant): Indolamine 2,3-deoxygenase enzymes (IDO-1 and IDO-2) play important counter-regulatory roles in the immune system. IDO-mediated tryptophan catabolism induces T cell suppression, which plays a physiological role in suppr
essing autoimmune and allergic diseases, as… More