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STTR Phase I: Magnetic Nanoparticle Microfluidics for High Efficient Capture,…

Award Information

Agency:
National Science Foundation
Branch:
N/A
Award ID:
88530
Program Year/Program:
2008 / STTR
Agency Tracking Number:
0810626
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2008
Title: STTR Phase I: Magnetic Nanoparticle Microfluidics for High Efficient Capture, Separation and Concetration of Foodborne Pathogens
Agency: NSF
Contract: 0810626
Award Amount: $150,000.00
 

Abstract:

This Small Business Technology Transfer Phase I research demonstrates the feasibility to use the new generation of oxide magnetic nanoparticles for rapid and high efficient separation of foodborne pathogens. Rapid detection of foodborne pathogens is urgently needed to ensure food safety and security, and in developing new detection methods, separation of target pathogens at ultra low concentrations (1 - 100 cfu/mL) from food is very critical. The recently developed nanoparticles (4 ? 50 nm) with high magnetization value and well controlled size and surface chemistry show great potential for their use in bioseparation. Therefore, the objective of this project is to apply new oxide magnetic nanoparticles to a portable, inexpensive magnetic separator for rapid and high efficient separation of foodborne pathogens. In Phase I of this project, E. coli O157:H7 will be used as the target bacterium to test magnetic nanoparticles with different sizes and structures, to evaluate antibody-nanoparticle conjugates, different buffer solutions and protocols. The broader impacts of this research are to improve the safety and security of the nation?s food supply and biological systems. The proposed new technology will greatly enhance the rapid detection of pathogens in food products, and thus to reduce foodborne illnesses. Also, the outcome of this proposed research should provide direct economic benefits to the food industry in terms of reduced product recalls and international trade barrier due to microbial contamination.

Principal Investigator:

Yongqiang A. Wang
PhD
4794446028
awang@oceannanotech.com

Business Contact:

Yongqiang A. Wang
PhD
4794446028
awang@oceannanotech.com
Small Business Information at Submission:

Ocean NanoTech, LLC
700 Research Center Blvd Fayetteville, AR 72701

EIN/Tax ID: 270097569
DUNS: N/A
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Research Institution Information:
University of Arkansas Fayetteville Campus
120 Ozark Hall
Fayettteville, AR 72701
Contact: Rosemary Ruff
Contact Phone: (479) 575-3845
RI Type: Nonprofit college or university