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Nanoparticle Based Magnetic Microfluidic concentrator (MMC)

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
89491
Program Year/Program:
2008 / STTR
Agency Tracking Number:
CA130986
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2008
Title: Nanoparticle Based Magnetic Microfluidic concentrator (MMC)
Agency: HHS
Contract: 1R41CA130986-01
Award Amount: $100,000.00
 

Abstract:

DESCRIPTION (provided by applicant): Enriched abnormal exfoliated cells and biomolecules will enable genomic, proteomic, and epigenomic analyses to detect cancer-specific alterations in expressed genes, protein/peptide profiles, and epigenetic markers. The ability to carry out such enrichment and analyses in a routine way using body fluids may lead to improvements in cancer detection. This NIH SBIR Phase I proposal is to develop a high throughput and high enrichment factor system for the enrichment o f rare cancer cells and cell fragments. In phase I, the enrichment of cancer cell, cancer protein and all DNAs will be studied through our model system. In phase II, the cancer cells and cell fragment in body fluids will be used to optimize this system. Th e final deliverables will include a MMC, antibody immobilized MNPs and all necessary protocols.

Principal Investigator:

Business Contact:


AWANG@OCEANNANOTECH.COM
Small Business Information at Submission:

OCEAN NANOTECH, LLC
OCEAN NANOTECH, LLC 2143 Worth Lane SPRINGDALE, AR 72764

EIN/Tax ID: 270097569
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No