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PURIFICATION OF MARINE OIL-DERIVED POLYUNSATURATES

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
4946
Program Year/Program:
1987 / SBIR
Agency Tracking Number:
4946
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Ocean Organics Inc.
1 Main Street Hope, RI 02831
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 2
Fiscal Year: 1987
Title: PURIFICATION OF MARINE OIL-DERIVED POLYUNSATURATES
Agency: HHS
Contract: N/A
Award Amount: $396,000.00
 

Abstract:

THE SPECIFIC AIM OF THIS PROJECT IS TO DEVELOP TECHNOLOGIC- ALLY EFFICIENT AND COST-EFFECTIVE METHODS FOR THE SEPARATIONAND PURIFICATION OF MULTIGRAM QUANTITIES OF HIGH POLYUN- SATURATES (E.G., EICOSAPNOIC ACID, EPA, C20:5W3; DOCOSAHEXAENOIC ACID, DHA, C22:6W3; AND ESTERS) FROM MARINE/FISH OILS, WITH THE LONG-TERM OBJECTIVE OF MAKING THESE AND POSSIBLY OTHER HIGH POLYUNSATURATES AVAILABLE FOR A WAITING MARKET. THE HEALTH-RELATEDNESS OF THE PROPOSED PROJECT IS DUE TO THE FACT THAT EPA AND DHA ARE MODULATORS OF THE BIOSYNTHESIS OF PROSTAGLANDINS AND OTHER EICOSANOIDS OF EXPANDING PHYSIOLOGIC AND PATHOPHYSIOLOGIC INTEREST IN BIOLOGY AND MEDICINE; AFFECT PHYSICAL PROPERTIES OF MEMBRANEGLYCEROPHOSPHOLIPIDS; AND, IN NATIVE (ESKIMOS, CERTAIN COASTAL DWELLERS) AND EXPERIMENTAL DIETS RICH IN EPA AND DHA, HAVE ANTITHROMBOTIC AND CARDIO-PROTECTIVE EFFECTS. THEMETHODOLOGY FOR THE SEPARATION AND PURIFICATION OF EPA, DHA,AND OTHER MARINE OIL-DERIVED POLYUNSATURATES WOULD FOCUS ON STATE-OF-THE-ART INNOVATIONS (SYSTEMS AND SEPARATION SCIENCE) IN PREPARATIVE HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY.

Principal Investigator:

William R Russo
Principal Investigator
4018289400

Business Contact:

Small Business Information at Submission:

Ocean Organics Inc.
1 Main Street Hope, RI 02831

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No