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SBIR Phase I: ChromArray, Chrosome Analysis Wafer

Award Information

National Science Foundation
Award ID:
Program Year/Program:
2003 / SBIR
Agency Tracking Number:
Solicitation Year:
Solicitation Topic Code:
Solicitation Number:
Small Business Information
Oceanit Laboratories, Inc.
Oceanit Center 828 Fort Street Mall, Suite 600 Honolulu, HI 96813-
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Phase 1
Fiscal Year: 2003
Title: SBIR Phase I: ChromArray, Chrosome Analysis Wafer
Agency: NSF
Contract: 0319105
Award Amount: $99,920.00


This Small Business Innovation Research (SBIR) Phase I project proposes a new technique for rapid Karyotyping based on a "ChromArray" device, which would allow the collection of a large number of chromosome spreads in a precise array. By collecting the inherent spectrum of chromosomes, the addition of dye is not necessary. Each physical coordinate within the karyotype would contain a third axis (spectra), adding further criteria for automated karyotpying of large number of chromosome spreads simultaneously. This project will investigate a technique of karyotyping that permits rapid identification of chromosomal alterations, thereby identifying chromosomal abnormalities of a large array of chromosome samples simultaneously. Therefore a large number of cells from the human body (of which there are 200 cell types) can be studied, to screen for genetic disorders. The commercial application of this project is in the area of human healthcare. The use of chromarray technology and near field optical microscopy would impact a variety of clinical disease assays when completely implemented.

Principal Investigator:

Daniel O'Connell

Business Contact:

Small Business Information at Submission:

Oceanit Laboratories
1001 Bishop Street Honolulu, HI 96813

Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No