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SPECIFIC LONG-TERM OBJECTIVES ARE TO DEVELOP A DIAGNOSTIC TEST THAT WILL DETECT…

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
4891
Program Year/Program:
1986 / SBIR
Agency Tracking Number:
4891
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
O'connor Diagnostics Corp
324 East Wisconsin Ave Milwaukee, WI 53202
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1986
Title: SPECIFIC LONG-TERM OBJECTIVES ARE TO DEVELOP A DIAGNOSTIC TEST THAT WILL DETECT THE OCCURRENCE OF DIABETIC NEPHROPATHYAT AN EARLIER, TREATABLE PHASE.
Agency: HHS
Contract: N/A
Award Amount: $50,000.00
 

Abstract:

SPECIFIC LONG-TERM OBJECTIVES ARE TO DEVELOP A DIAGNOSTIC TEST THAT WILL DETECT THE OCCURRENCE OF DIABETIC NEPHROPATHYAT AN EARLIER, TREATABLE PHASE. THE DEVELOPED TEST REAGENT WILL BE MONOCLONAL ANTIBODIES TO ANTIGENS THAT ARE ASSOCIA- TED WITH DIABETIC NEPHROPATHY. THE SOURCE OF DIABETIC NEPHROTIC-RELATED ANTIGEN WILL BE CIRCULATING IMMUNE COMPLEXES THAT OCCUR IN THE BLOOD OF ALL HUMAN DIABETICS DEVELOPING THIS PROGRESSIVE KIDNEY DISEASE. PHASE I WILL INVOLVE ORGANIZATION AND COLLECTION OF ALL RESEARCH DATA TO BEGIN SCREENING OF HYBRIDOMAS FOR ANTIBODY PRODUCTION TO POTENTIAL MARKERS FOR HUMAN DIABETIC NEPHROPATHY. PHASE II WILL ENTAIL ANTIGEN CHARACTERIZATION, OCCURENCE, SPECIFICITY, AND RELATEDNESS TO OTHER DISEASES. AS DIABETICNEPHROPATHY AFFECTS HALF OF THE TYPE I DIABETICS, A SPECIFIC, RAPID, INEXPENSIVE TEST PERFORMED AT THE CLINICAL LEVEL HAS ENORMOUS MEDICAL IMPORTANCE FOR DIAGNOSING AND EVENTUALLY TREATING NEPHROPATHIC DIABETICS. PRESENTLY THE ONLY RELIABLE DIAGNOSTIC TEST IS PROTEINURIA WHICH, TRAGICALLY, DETECTS KIDNEY DISEASE AT AN IRREVERSIBLE STAGE.

Principal Investigator:

Howard sean o'connor
PRINCIPAL INVESTIGATOR
4142722676

Business Contact:

Small Business Information at Submission:

O'connor Diagnostics Corp
324 East Wisconsin Ave Milwaukee, WI 53202

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No