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A NEW RAPID TEST FOR SALMONELLA DETECTION USING LIPOSOME -ENTRAPPED MOLECULES

Award Information

Agency:
Department of Agriculture
Branch:
N/A
Award ID:
4628
Program Year/Program:
1987 / SBIR
Agency Tracking Number:
4628
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Ohmicron Corp.
375 Pheasant Run Newtown, PA 18940
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 2
Fiscal Year: 1987
Title: A NEW RAPID TEST FOR SALMONELLA DETECTION USING LIPOSOME -ENTRAPPED MOLECULES
Agency: USDA
Contract: N/A
Award Amount: $200,000.00
 

Abstract:

THE TESTING FOR SALMONELLA CURRENTLY INVOLVES METHODOLOGY THAT REQUIRES 3-8 DAYS TO COMPLETE AND A FAIRLY SOPHISTICAT ED SKILL LEVEL TO PERFORM. THIS PROJECT IS DESIGNED TO D DEVELOP BOTH MANUAL AND BIOSENSOR-BASED HOMOGENEOUS ASSAYS THAT WILL REDUCE THE DETECTION TIME OF SALMONELLA TO WITHIN 24 HOURS AND BE TECHNICALLY SIMPLER TO PERFORM. THE NOVEL ASPECT IS THE USE OF A LIMPSOME-ENCAPSULATED ENZYME. THE ENZYME WILL BE RELEASED FROM THE LIPOSOME UPON THE INTER ACTION OF SALMONELLA ORGANISMS WITH A MONOCLONAL ANTIBODY ON THE LIPOSOME SURFACE IN THE PRESENCE OF COMPLEMENT. THE ENZYME WOULD NOW BE FREE TO GENERATE A PRODUCT WHICH WOULD CAUSE A COLOR CHANGE IN THE MANUAL TEST AND A MEASURABLE CONDUCTIVITY CHANGE IN THE BIOSENSOR-BASE TEST.

Principal Investigator:


0

Business Contact:

Dr. mark malmros
Small Business Information at Submission:

Ohmicron Corp.
108 West Franklin Ave Pennington, NJ 08534

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No