USA flag logo/image

An Official Website of the United States Government

SBIR Phase I: A Label-Free SERS-Capture Assay in Microchips for Biological…

Award Information

Agency:
National Science Foundation
Branch:
N/A
Award ID:
88384
Program Year/Program:
2008 / SBIR
Agency Tracking Number:
0810335
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Real-Time Analyzers
362 INDUSTRIAL PARK RD, #8 MIDDLETOWN, CT -
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2008
Title: SBIR Phase I: A Label-Free SERS-Capture Assay in Microchips for Biological Warfare Agents
Agency: NSF
Contract: 0810335
Award Amount: $99,998.00
 

Abstract:

This Small Business Innovation Research Phase I project develops assay chips that can detect, identify, and quantify the presence of Category A or B bioagents at the required sensitivity within 10 minutes. The assay chips will employ silver particles in a porous sol-gel to selectively extract and bind a specific bioagent with detection using surface-enhanced Raman spectroscopy (SERS). The chips will be part of an analyzer that also includes an aerosol collector and a field usable Raman spectrometer. Feasibility of the approach will be demonstrated during Phase I by developing the silver functionalization method to bind Bacillus cereus and Bacillus subtilis spores, and to detect the capture event by SERS. During the Phase II project, assay chips will be developed and field-tested for several Category A or B bioagents. The broader impacts of this research an enchancement of our ability to monitor public places targeted by terrorists, and to implement rapid response and countermeasures. This information will save lives and substantially reduce the terror associated with such attacks. The device can also be adapted to detect more common Category B pathogens regarding food and water safety (e.g. E. coli 0157:H7).

Principal Investigator:

Frank E. Inscore
PhD
8606359800
inscore@rta.biz

Business Contact:

Frank E. Inscore
PhD
8606359800
inscore@rta.biz
Small Business Information at Submission:

REAL-TIME ANALYZERS, INCORPORATED
362 INDUSTRIAL PARK RD #8 MIDDLETOWN, CT 06457

EIN/Tax ID: 061633295
DUNS: N/A
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No