USA flag logo/image

An Official Website of the United States Government

VITRIFICATION FOR TISSUE ENGINEERED BLOOD VESSELS

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
54051
Program Year/Program:
2001 / SBIR
Agency Tracking Number:
1R43HL066688-01
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
ORGAN RECOVERY SYSTEMS, INC.
ORGAN RECOVERY SYSTEMS, INC. 701 E BAY ST, SUITE 433 CHARLESTON, SC 29403-0500
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2001
Title: VITRIFICATION FOR TISSUE ENGINEERED BLOOD VESSELS
Agency: HHS
Contract: N/A
Award Amount: $100,000.00
 

Abstract:

DESCRIPTION (Verbatim From Applicant's Abstract): Effective methods of preservation are irnportant for the remerging technology of tissue engineering. We recently demonstrated, for the first time, that vitrification can have a salutary effect on the cryopreservation of a complete tissue, rabbit jugular vein, which otherwise sustains significant injury from freezing. Restriction of the amount and size of ice crystal formation during cryopreservation can be achieved by promotion of amorphous solidification (vitrification) rather than crystallization In this Phase I SBIR proposal, the primary objective is to test the feasibility of employing vitrification for long-term storage of tissue engineered blood vessels (TEBV). The effects of vitrification and conventional cryopreservation involving ice formation will be assessed using biomechanical tests, cell viability assays and vascular physiology methods. If vitrification is shown to be feasible for storage of TEBVs, these studies will be extended to a Phase II SBIR proposal to include in vivo testing of the Duke University TEBVs and TEBVs being developed by other organizations. PROPOSED COMMERCIAL APPLICATION: Customers are tissue engineering, tissue processing and banking organizations, and companies supplying reagents and biological materials to research organizations. The tissue engineering industry addresses diseases and disorders associated with over $500 billion expended annually in the U.S. for health care costs.

Principal Investigator:

Ying C. Song

Business Contact:


8437226756
Small Business Information at Submission:

ORGAN RECOVERY SYSTEMS, INC.
2570 E DEVON AVE DES PLAINES, IL 60018

EIN/Tax ID: 364256620
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No