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Company Information:

Company Name: ORGANIX, INC.
City: WOBURN
State: MA
Zip+4: 01801-
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Website URL: N/A
Phone: N/A

Award Totals:

Program/Phase Award Amount ($) Number of Awards
SBIR Phase I $3,109,425.00 11
SBIR Phase II $2,296,515.00 2

Award List:

Peripheral Narcotic Antagonists--14-Aminomorphinones

Award Year / Program / Phase: 1995 / SBIR / Phase I
Agency: HHS
Principal Investigator: Raj Razdan
Award Amount: $100,000.00
Abstract:
Constipation is the most frequently encountered side effect in the chronic use of opiates to treatthe maintenance of opiate addicts. An opiate antagonist with only peripheral activity, when co-adminwould prevent or substantially reduce constipation. Standard opiate antagonists as their… More

Spect Imaging Agent for Parkinsons Disease

Award Year / Program / Phase: 1995 / SBIR / Phase I
Agency: HHS
Principal Investigator: Peter Meltzer
Award Amount: $100,000.00
Abstract:
There is currently no presymptomatic clinical diagnostic tool for the diagnosis of Parkinson's disedepletion of the dopamine transporter (DAT) in the striatum is a well-established marker of Pd and cdiagnosis of Pd can be achieved by a measure of DAT depletion. We will design and synthesize a… More

DESIGN OF A NOVEL COCAINE ANTAGONIST

Award Year / Program / Phase: 1996 / SBIR / Phase I
Agency: HHS
Principal Investigator:
Award Amount: $100,000.00

INDOLE ANALOGS AS NOVEL TREATMENTS FOR OCD

Award Year / Program / Phase: 2002 / SBIR / Phase I
Agency: HHS
Principal Investigator: Howard P. Sard
Award Amount: $109,197.00
Abstract:
Obsessive Compulsive Disorder (OCD) is a serious mental illness that affects millions of people throughout the world. Existing therapies for OCD show limited efficacy, can possess troubling side effects, and often require long-term treatment. Discovery of a new treatment for OCD would have… More

Indole Analogs as Novel Appetite Suppressants

Award Year / Program / Phase: 2003 / SBIR / Phase I
Agency: HHS
Principal Investigator: Howard P. Sard
Award Amount: $559,580.00
Abstract:
DESCRIPTION (provided by applicant): Obesity affects millions of people in the U.S. and worldwide, and this disease has enormous health and economic consequences for our society. Existing treatments show limited efficacy, can possess troubling side effects, and often require long-term therapy.… More

Novel THC/Anandamide Hybrids as Appetite Suppressants

Award Year / Program / Phase: 2005 / SBIR / Phase I
Agency: HHS
Principal Investigator: Anu Mahadevan
Award Amount: $504,211.00
Abstract:
Obesity has reached epidemic proportions and in a year about 300,000 people die of obesity-related diseases. Annual medical spending due to obesity and overweight is about $117 billion. There is an urgent need to discover effective drugs to treat this disease since existing drugs have modest… More

Indole Analogs as Novel Treatments for OCD

Award Year / Program / Phase: 2006 / SBIR / Phase II
Agency: HHS
Principal Investigator: Howard P. Sard
Award Amount: $1,464,922.00
Abstract:
DESCRIPTION (provided by applicant): Obsessive Compulsive Disorder (OCD) is a serious mental illness that affects millions of people throughout the world. Existing therapies for OCD show limited efficacy, can possess troubling side effects, and often require long-term treatment. Discovery of a new… More

Indole Analogs as Novel Appetite Suppressants

Award Year / Program / Phase: 2007 / SBIR / Phase II
Agency: HHS
Principal Investigator: Howard P. Sard
Award Amount: $831,593.00
Abstract:
DESCRIPTION (provided by applicant): Obesity affects millions of people in the U.S. and worldwide, and this disease has enormous health and economic consequences for our society. Existing treatments show limited efficacy, can possess troubling side effects , and often require long-term therapy.… More

CB2 Agonists for Treatment of Neuropathic Pain.

Award Year / Program / Phase: 2008 / SBIR / Phase I
Agency: HHS
Principal Investigator:
Award Amount: $130,505.00
Abstract:
DESCRIPTION (provided by applicant): Neuropathic pain is a type of chronic pain state caused by injury or disease to the nervous system. Annual medical spending due to pain has been estimated to be over 100 billion. Currently there are no medications ava ilable to prevent or cure this devastating… More

Benzodiazepine Analogs as Novel Treatments for Catatonia

Award Year / Program / Phase: 2011 / SBIR / Phase I
Agency: HHS
Principal Investigator: Howard P. Sard – 781-932-4142
Award Amount: $686,852.00
Abstract:
DESCRIPTION (provided by applicant): Catatonia is a widespread and serious syndrome characterized by mutism, stupor, refusal to eat or drink, posturing, and hypokinesis, and affects a broad range of psychiatric and other patients in the US and worldwide. Untreated or poorly managed catatonic… More

The first reversible radioligand for the hVMAT2 [3H]reserpine binding site

Award Year / Program / Phase: 2012 / SBIR / Phase I
Agency: HHS
Principal Investigator: Peter C. Meltzer – 781-932-4142
Award Amount: $250,001.00
Abstract:
DESCRIPTION (provided by applicant): Abuse of methamphetamine (MA) is a major health problem. About 10 million Americans have used MA at least once. Chronic MA use has far reaching health consequences and has a tremendous societal impact. The National Institute on Drug Abuse has expressed… More

Pharmacological Suppression of Rod Opsin as Therapy for Retinitis Pigmentosa

Award Year / Program / Phase: 2013 / SBIR / Phase I
Agency: HHS
Principal Investigator: Anuradha Mahadevan – 781-932-4142
Award Amount: $289,823.00
Abstract:
DESCRIPTION (provided by applicant): Metastasis of aggressive breast cancer is a devastating and ultimately fatal condition. The current first- line agents which are used to treat breast cancer metastasis primarily target tumor growth. These drugs produceonly modest increases in survival in patients… More

Vaginal Tactile Imager for Pelvic Floor Biomechanical Assessment

Award Year / Program / Phase: 2013 / SBIR / Phase I
Agency: HHS
Principal Investigator: Anuradha Mahadevan – 781-932-4142
Award Amount: $279,256.00
Abstract:
DESCRIPTION (provided by applicant): Chronic pain can result from various disease conditions and about 45% of the U. S. population seeks medical help for treatment of pain. Neuropathic pain is a type of chronic pain which is very difficult to treat, and most patients do not get adequate relief. A… More